Table 1 Comparison of patient characteristics by sex
From: Sex-specific prevalence and outcomes of frailty in critically ill patients
Unmatched | Matched | ||||||
|---|---|---|---|---|---|---|---|
Male (N = 9254) | Female (N = 5984) | p value | Standardized difference | Male (N = 5908) | Female (N = 5908) | Standardized difference | |
Patient characteristics | |||||||
Age (mean [SD]), years | 58.2 [16.4] | 57.3 [17.0] | 0.001 | 0.055 | 57.3 [16.7] | 57.3 [17.0] | 0.001* |
ICU type | < 0.001 | ||||||
Academic | 4971 (54%) | 2551 (43%) | 0.227 | 2941 (50%) | 2522 (43%) | 0.143 | |
Tertiary | 1449 (16%) | 1047 (18%) | 0.053 | 999 (17%) | 1042 (18%) | 0.020 | |
Community | 1540 (17%) | 1246 (21%) | 0.107 | 1068 (18%) | 1226 (21%) | 0.069 | |
Regional | 1294 (14%) | 1140 (19%) | 0.137 | 900 (15%) | 1118 (19%) | 0.098 | |
Admission category, (n;%) | < 0.001 | ||||||
Medical/non-operative | 5277 (57%) | 3907 (65%) | 0.172 | 3676 (62%) | 3850 (65%) | 0.061 | |
Elective surgical | 2353 (25%) | 1094 (18%) | 0.176 | 1222 (21%) | 1084 (18%) | 0.057 | |
Emergency surgical | 1576 (17%) | 948 (16%) | 0.004 | 967 (16%) | 943 (16%) | 0.011 | |
No admission category assigned | 48 (0.5%) | 35 (0.5%) | 0.008 | 43 (0.7%) | 31 (0.5%) | 0.029 | |
Admission classification, (n;%) | < 0.001 | ||||||
Medical | 4154 (45%) | 3352 (56%) | 0.228 | 2902 (49%) | 3308 (56%) | 0.138 | |
Neurology | 690 (7%) | 498 (5%) | 0.031 | 512 (9%) | 491 (8%) | 0.013 | |
Surgical | 3796 (41%) | 1954 (33%) | 0.178 | 2091 (35%) | 1935 (33%) | 0.039 | |
Trauma | 556 (6%) | 144 (2%) | 0.180 | 354 (6%) | 142 (2%) | 0.180 | |
No admission classification assigned | 58 (0.6%) | 36 (0.6%) | 0.004 | 49 (0.8%) | 32 (0.5%) | 0.029 | |
Diagnostic category, (n;%) | < 0.001 | ||||||
Cardiovascular | 3216 (35%) | 1552 (26%) | 0.194 | 1508 (26%) | 1532 (26%) | 0.009* | |
Respiratory | 1956 (21%) | 1531 (26%) | 0.106 | 1495 (25%) | 1514 (26%) | 0.008* | |
Gastrointestinal/hepatic | 1040 (11%) | 717 (12%) | 0.022 | 691 (12%) | 706 (12%) | 0.008* | |
Neurologic | 1416 (15%) | 1120 (19%) | 0.091 | 1104 (19%) | 1105 (19%) | 0* | |
Other diagnosis | 1504 (16%) | 947 (16%) | 0.010 | 993 (17%) | 939 (16%) | 0.025* | |
No diagnostic category assigned | 122 (1%) | 117 (2%) | 0.051 | 117 (2%) | 112 (2%) | 0.007* | |
APACHE II score, (mean [SD]) | 18.4 [8.1] | 19.0 [8.1] | < 0.001 | 0.074 | 19.0 [8.3] | 19.0 [8.1] | 0* |
Admission SOFA score, (mean [SD]) | 6.5 [3.7] | 6.1 [3.8] | < 0.001 | 0.114 | 6.5 [3.8] | 6.1 [3.8] | 0.116 |
Pre-ICU hospitalization duration (mean [SD]), days | 4.1 [15.9] | 3.7 [15.1] | < 0.001 | 0.023 | 3.7 [13.7] | 3.6 [12.7] | 0.010* |
Frailty | 2282 (25%) | 1917 (32%) | < 0.001 | 0.164 | 1575 (27%) | 1890 (32%) | 0.117 |
CFS score (median [IQR]) | 3 [2–4] | 4 [2–5] | < 0.001 | 0.147 | 3 [2–5] | 4 [2–5] | 0.122 |
APACHE chronic health condition variables | |||||||
Diabetes mellitus | 2168 (23%) | 1331 (22%) | 0.09 | 0.029 | 1339 (23%) | 1314 (22%) | 0.010 |
Acute renal failure on admission | 1802 (19%) | 1210 (20%) | 0.3 | 0.020 | 1244 (21%) | 1199 (20%) | 0.019 |
Respiratory insufficiency | 950 (10%) | 859 (14%) | < 0.001 | 0.125 | 827 (14%) | 849 (14%) | 0.011* |
Congestive heart failure | 746 (8%) | 430 (7%) | 0.05 | 0.036 | 468 (8%) | 421 (7%) | 0.030 |
Immunosuppression | 660 (7%) | 504 (8%) | 0.003 | 0.049 | 459 (8%) | 500 (8%) | 0.026 |
Cirrhosis | 389 (4%) | 261 (4%) | 0.6 | 0.008 | 264 (4%) | 258 (4%) | 0.005 |
Metastatic carcinoma | 282 (3%) | 186 (3%) | 0.8 | 0 | 181 (3%) | 181 (3%) | 0 |
Hepatic failure | 205 (2%) | 166 (3%) | 0.03 | 0.035 | 146 (2%) | 163 (3%) | 0.018 |
Lymphoma | 81 (0.9%) | 38 (0.6%) | 0.1 | 0.027 | 51 (0.9%) | 38 (0.6%) | 0.025 |
Leukemia | 77 (0.8%) | 36 (0.6%) | 0.1 | 0.025 | 45 (0.8%) | 36 (0.6%) | 0.018 |
Acquired immunodeficiency syndrome | 37 (0.4%) | 16 (0.3%) | 0.2 | 0.023 | 25 (0.4%) | 16 (0.3%) | 0.026 |