Table 1 Patient characteristics
Total (N = 844) | D5W (n = 365) | Saline (n = 479) | p value | |
|---|---|---|---|---|
Age, years | 69 (55–77) | 68 (56–75) | 69 (55–78) | 0.313 |
Male sex | 584 (69.2) | 244 (66.8) | 340 (71.0) | 0.202 |
Height, cm | 164 (157–170) | 164 (158–170) | 164 (157–170) | 0.593 |
Weight, kg | 60 (50–70) | 61 (51–70) | 60 (50–70) | 0.62 |
Body mass index | 22 (20–25) | 23 (20–25) | 22 (20–25) | 0.295 |
Comorbidity | ||||
Heart failure | 8 (0.9) | 2 (0.5) | 6 (1.3) | 0.477 |
Respiratory failure | 17 (2.0) | 5 (1.4) | 12 (2.5) | 0.325 |
Liver cirrhosis | 30 (3.6) | 16 (4.4) | 14 (2.9) | 0.266 |
Hematologic malignancy | 45 (5.3) | 20 (5.5) | 25 (5.2) | 0.878 |
Metastatic malignancy | 34 (4.0) | 12 (3.3) | 22 (4.6) | 0.381 |
Immunosuppression | 95 (11.3) | 39 (10.7) | 56 (11.7) | 0.662 |
Time from hospitalization to ICU, days | 2 (0–7) | 3 (0–8) | 1 (0–6) | 0.005 |
Patient category | 0.005 | |||
Planned surgical | 291 (34.5) | 150 (41.1) | 141 (29.4) | |
Nonplanned surgical | 212 (25.1) | 83 (22.7) | 129 (26.9) | |
Medical from ward | 185 (21.9) | 75 (20.5) | 110 (23.0) | |
Medical from ED | 156 (18.5) | 57 (15.6) | 99 (20.7) | |
Main damaged organ | 0.745 | |||
Cardiovascular | 342 (40.5) | 156 (42.7) | 186 (38.8) | |
Neurologic | 153 (18.1) | 65 (17.8) | 88 (18.4) | |
Respiratory | 127 (15.0) | 49 (13.4) | 78 (16.3) | |
Digestive | 120 (14.2) | 51 (14.0) | 69 (14.4) | |
Other | 102 (12.1) | 44 (12.1) | 58 (12.1) | |
APACHE III score | 71 (56–88) | 71 (57–86) | 72 (54–88) | 0.916 |
Data at ICU admission | ||||
Sodium, mmol/L | 140 (137–142) | 140 (137–142) | 140 (137–143) | 0.274 |
Chloride, mmol/L | 107 (103–111) | 108 (104–111) | 107 (103–111) | 0.105 |
Blood glucose, mg/dL | 137 (115–169) | 136 (113–169) | 138 (115–169) | 0.525 |
Baseline creatinine, mg/dL | 0.85 (0.74–0.99) | 0.84 (0.72–0.98) | 0.85 (0.75–1.00) | 0.448 |