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Table 3 A) Demographic and clinical characteristics of the patients with flu syndrome with ARDS who underwent autopsy. B) Correlation between biomarkers of endothelial damage and hyaline membrane perimeter and the number of neutrophils in the alveolar septum in these patients

From: Endothelial glycocalyx shedding in the acute respiratory distress syndrome after flu syndrome

A) Characteristics of the patients who underwent autopsy
  Age (year) Gender Symptoms duration (days) PaO2/FiO2 ratio on admission Risk factors Time for death after admission (days)
Patient 1 34 Female 4 65 Overweight 1
Patient 2 53 Male 6 85 Smoking 2
Patient 3 37 Female 4 57 Obesity 5
Patient 4 55 Female 6 110 Obesity, diabetes, hypertension 9
B) Biomarkers and autopsy findings
Biomarker Hyaline membrane perimeter Number of neutrophils in alveolar septum
r p-value r p-value
Hyaluronan – 0.40 0.60 0.89 0.05
Thrombomodulin 0.89 0.05 – 0.30 0.69
Syndecan-1 0.87 0.13 – 0.17 0.83
  1. PaO2 partial pressure of arterial oxygen, FiO2 fraction of inspired oxygen, r coefficient of correlation