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Table 3 A) Demographic and clinical characteristics of the patients with flu syndrome with ARDS who underwent autopsy. B) Correlation between biomarkers of endothelial damage and hyaline membrane perimeter and the number of neutrophils in the alveolar septum in these patients

From: Endothelial glycocalyx shedding in the acute respiratory distress syndrome after flu syndrome

A) Characteristics of the patients who underwent autopsy

 

Age (year)

Gender

Symptoms duration (days)

PaO2/FiO2 ratio on admission

Risk factors

Time for death after admission (days)

Patient 1

34

Female

4

65

Overweight

1

Patient 2

53

Male

6

85

Smoking

2

Patient 3

37

Female

4

57

Obesity

5

Patient 4

55

Female

6

110

Obesity, diabetes, hypertension

9

B) Biomarkers and autopsy findings

Biomarker

Hyaline membrane perimeter

Number of neutrophils in alveolar septum

r

p-value

r

p-value

Hyaluronan

– 0.40

0.60

0.89

0.05

Thrombomodulin

0.89

0.05

– 0.30

0.69

Syndecan-1

0.87

0.13

– 0.17

0.83

  1. PaO2 partial pressure of arterial oxygen, FiO2 fraction of inspired oxygen, r coefficient of correlation