From: Endothelial glycocalyx shedding in the acute respiratory distress syndrome after flu syndrome
A) Characteristics of the patients who underwent autopsy | ||||||
Age (year) | Gender | Symptoms duration (days) | PaO2/FiO2 ratio on admission | Risk factors | Time for death after admission (days) | |
Patient 1 | 34 | Female | 4 | 65 | Overweight | 1 |
Patient 2 | 53 | Male | 6 | 85 | Smoking | 2 |
Patient 3 | 37 | Female | 4 | 57 | Obesity | 5 |
Patient 4 | 55 | Female | 6 | 110 | Obesity, diabetes, hypertension | 9 |
B) Biomarkers and autopsy findings | ||||||
Biomarker | Hyaline membrane perimeter | Number of neutrophils in alveolar septum | ||||
r | p-value | r | p-value | |||
Hyaluronan | – 0.40 | 0.60 | 0.89 | 0.05 | ||
Thrombomodulin | 0.89 | 0.05 | – 0.30 | 0.69 | ||
Syndecan-1 | 0.87 | 0.13 | – 0.17 | 0.83 |