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Table 1 Characteristics of the patients included in this investigation.

From: Endothelial glycocalyx shedding in the acute respiratory distress syndrome after flu syndrome

Characteristics Flu syndrome   p value
With ARDS
N = 30
Without ARDS
N = 36
Control
N = 35
 
Demographic
 Age (years), mean ± sd 44 ± 16 39 ± 17 44 ± 9 0.280
 Male gender, n (%) 17 (57) 15 (42) 18 (51) 0.700
Clinical presentation, n (%)
 Fever 28 (93) 32 (89) 0.680
 Cough 26 (87) 28 (78) 0.670
 Myalgia 18 (60) 27 (75) 0.280
 Dyspnea 29 (97) 14 (39) < 0.0001
 Symptoms duration; days, median (IQR) 5 (4–7) 4 (2–5) < 0.0001
Risk factors for severe presentation, n (%)
 Diabetes 05 (17) 02 (05) 0.430
 Hypertension 07 (23) 03 (08) 0.170
 Smoking 06 (20) 04 (11) 0.490
 Pulmonary disease 7 (23) 5 (14) 0.350
 Cardiac disease 2 (07) 2 (06) 1.000
 Neurologic disease 2 (07) 0 (00) 0.200
 Obesity 4 (13) 2 (06) 0.400
 Pregnancy 0 (00) 0 (00) 1.000
Physical examination
 Heart rate; bpm, mean ± sd 104 ± 21 86 ± 15 0.0009
 SBP; mmHg, mean ± sd 117 ± 21 119 ± 13 0.750
 DBP; mmHg, mean ± sd 73 ± 15 74 ± 8 0.700
Laboratory test
 Creatinine; mg/dl, median (IQR) 1.0 (0.8–1.6) 0.9 (0.8–1.2) 0.200
 Leukocytes; mm3, median (IQR) 6150 (3900–10100) 8350 (6300–10900) 0.050
 Influenza A IgM positive, n (%) 8 (27) 10 (28) 0.930
 Influenza A IgG positive, n (%) 30 (100) 35 (97) 1.000
 Influenza A RT-PCR positive, n/n(%) 12/23*(52) 03/25*(12) 0.020
 Influenza A RT-PCR or IgM positive, n (%) 17 (57) 13(36) 0.100
ARDS classification (Berlin criteria)
 Mild 6 (20)  
 Moderate 7 (23)  
 Severe 17 (57)  
 PaO2/FiO2 ratio; mmHg, median (IQR) 88 (65–140)  
 SOFA score, mean ± sd 7 ± 4  
Hospitalization rate, n (%) 30 (100) 06 (17) < 0.0001
In-hospital mortality rate, n (%) 14 (47) 00 (00) < 0.0001
  1. ARDS acute respiratory distress syndrome, sd standard deviation, IQR interquartile range, COPD chronic obstructive pulmonary disease, SBP systolic blood pressure, DBP diastolic blood pressure, IgM immunoglobulin M, IgG immunoglobulin G, RT-PCR real-time polymerase chain reaction, PaO2 partial pressure of arterial oxygen, FiO2 fraction of inspired oxygen, SOFA sequential organ failure assessment * proportion between the positive results and number of collected samples