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Table 1 Baseline characteristics of healthy controls and patients

From: Low levels of CD72 and CD100 expression on circulating lymphocytes in immunosuppressive phase of sepsis is associated with mortality in septic patients

Parameters Healthy Sepsis Septic shock P
Number 24 32 22 NA
Age (years) 47 (44–52) 51 (47–58) 47 (42–53) b 0.0474
Male, n (%) 17 (70.8%) 27 (84.4%) 16 (72.7%) b 0.423
WBC (10^9/L) 7.58 (7.34–7.88) 14.22 (12.68–16.57) 14.30 (13.22–15.77) b <0.0001
LC (10^9/L) 2.05 (1.90–2.15) 0.91 (0.77–1.09) 0.77 (0.68–0.92) a <0.0001
SOFA score NA 7 (5–10) 9 (7–11) a 0.047
SAPS II NA 29 (23–34) 36 (26–46) a 0.0311
APACHE II score NA 14 (12–17) 17 (15–21) a 0.008
CRP (mg/L) 1.3 (0.8–1.8) 126.7 (104.2–146.5) 131.9 (107.8–168.7) b <0.0001
IgM (g/L) 1.78 (1.48–2.15) 0.84 (0.76–1.0) 0.83 (0.72–0.93) b <0.0001
IL-6 (pg/ml) 10.6 (9.65–11.6) 80.0 (64.81–91.54) 88.58 (78.58–95.49) a <0.0001
IL-10 (pg/ml) 10.09 (9.14–11.17) 87.6 (75.88–100.9) 88.43 (72.94–98.84) b <0.0001
CD100+/CD4+ T cells % 80.9 (74.3–83.2) 67.0 (58.7–73.3) 52.8 (48.3–63.2) a <0.0001
CD100+/CD8+ T cells % 81.2 (76.2–85.5) 71.5 (62.7–77.4) 59.8 (48.0–75.4) a <0.0001
CD72+/CD19+ B cells % 72.8 (69.9–79.3) 67.9 (59.8–73.9) 58.5 (48.3–72.4) a <0.0001
28-day mortality, n (%) NA 7 (21.9%) 9 (40.9%) b 0.132
  1. Data are shown as median (interquartile ranges), frequencies and percentages. ANOVA and Kruskal-Wallis tests were performed for multi-group comparisons. aDenotes P < .05 and bdenotes P > .05 comparing sepsis group and septic shock group. NA Not applicable, WBC Counts of white blood cell, LC Counts of lymphocyte, SOFA Sequential organ failure assessment, SAPS II Simplified acute physiology score II, APACHE II Acute physiology and chronic health evaluation II, IgM Immunoglobulin M, CRP C-reaction protein, IL Interleukin