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Table 1 Baseline characteristics of healthy controls and patients

From: Low levels of CD72 and CD100 expression on circulating lymphocytes in immunosuppressive phase of sepsis is associated with mortality in septic patients

Parameters

Healthy

Sepsis

Septic shock

P

Number

24

32

22

NA

Age (years)

47 (44–52)

51 (47–58)

47 (42–53) b

0.0474

Male, n (%)

17 (70.8%)

27 (84.4%)

16 (72.7%) b

0.423

WBC (10^9/L)

7.58 (7.34–7.88)

14.22 (12.68–16.57)

14.30 (13.22–15.77) b

<0.0001

LC (10^9/L)

2.05 (1.90–2.15)

0.91 (0.77–1.09)

0.77 (0.68–0.92) a

<0.0001

SOFA score

NA

7 (5–10)

9 (7–11) a

0.047

SAPS II

NA

29 (23–34)

36 (26–46) a

0.0311

APACHE II score

NA

14 (12–17)

17 (15–21) a

0.008

CRP (mg/L)

1.3 (0.8–1.8)

126.7 (104.2–146.5)

131.9 (107.8–168.7) b

<0.0001

IgM (g/L)

1.78 (1.48–2.15)

0.84 (0.76–1.0)

0.83 (0.72–0.93) b

<0.0001

IL-6 (pg/ml)

10.6 (9.65–11.6)

80.0 (64.81–91.54)

88.58 (78.58–95.49) a

<0.0001

IL-10 (pg/ml)

10.09 (9.14–11.17)

87.6 (75.88–100.9)

88.43 (72.94–98.84) b

<0.0001

CD100+/CD4+ T cells %

80.9 (74.3–83.2)

67.0 (58.7–73.3)

52.8 (48.3–63.2) a

<0.0001

CD100+/CD8+ T cells %

81.2 (76.2–85.5)

71.5 (62.7–77.4)

59.8 (48.0–75.4) a

<0.0001

CD72+/CD19+ B cells %

72.8 (69.9–79.3)

67.9 (59.8–73.9)

58.5 (48.3–72.4) a

<0.0001

28-day mortality, n (%)

NA

7 (21.9%)

9 (40.9%) b

0.132

  1. Data are shown as median (interquartile ranges), frequencies and percentages. ANOVA and Kruskal-Wallis tests were performed for multi-group comparisons. aDenotes P < .05 and bdenotes P > .05 comparing sepsis group and septic shock group. NA Not applicable, WBC Counts of white blood cell, LC Counts of lymphocyte, SOFA Sequential organ failure assessment, SAPS II Simplified acute physiology score II, APACHE II Acute physiology and chronic health evaluation II, IgM Immunoglobulin M, CRP C-reaction protein, IL Interleukin