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Table 2 Univariate and multivariable comparisons of cases with favourable and unfavourable neurological outcomes

From: Extracorporeal cardiopulmonary resuscitation without target temperature management for out-of-hospital cardiac arrest patients prolongs the therapeutic time window: a retrospective analysis of a nationwide multicentre observational study in Japan

Variables Favourable outcomes (CPC 1–2; n = 412) Unfavourable outcomes (CPC 3–5; n = 2173) Univariate P value Multivariable P value OR (95% CI)
Age (years) 64 (52–74) 77 (66–85) < 0.001 < 0.001 0.947 (0.935–0.958)
Male (%) 312 (76%) 1402 (65%) < 0.001 0.689 1.076 (0.751–1.543)
BCPR (%) 241 (58%) 906 (42%) < 0.001 < 0.001 3.109 (2.221–4.352)
SR (%) 203 (49%) 476 (22%) < 0.001 < 0.001 4.572 (3.184–6.564)
NLT (min)a 11 (5–18) 43 (30–56) < 0.001 < 0.001 0.860 (0.847–0.874)
ECPR (%) 22 (5%) 285 (13%) < 0.001 < 0.001 3.782 (1.852–7.723)
  1. Values are median (interquartile range) or n (%) of cases
  2. CPC cerebral performance category, OR odds ratio, CI confidence interval, BCPR bystander cardiopulmonary resuscitation, SR shockable rhythm, NLT no and low-flow time, ECPR extracorporeal cardiopulmonary resuscitation
  3. aDefined as the interval from witnessed OHCA to start of reperfusion (start of extracorporeal membrane oxygenation for ECPR or return of spontaneous circulation for CCPR)