Table 1 Differences in clinical studies
From: Oxygen administration in patients recovering from cardiac arrest: a narrative review
|  | Type of study | Primary outcome | In-hospital mortality | OR or RR for in-hospital mortality | Effect of hyperoxia | PaO2 ≥ (>) 300 mmHg | Hyperoxia ≤ 4–24 h | PaO2 value for analysis | |
|---|---|---|---|---|---|---|---|---|---|
Hyperoxia | Control | ||||||||
Kilgannon et al. (2010) [7] | Retrospective | In-hospital mortality | 63% | 45% | 1.8 (1.5–2.2) | Unfavorable | Yes | Yes | Highest |
Kilgannon et al. (2011) [40] | Retrospective | In-hospital mortality |  |  | 1.69 (1.56–2.07) | Unfavorable |  | Yes | Highest |
Bellomo et al. (2011) [45] | Retrospective | In-hospital mortality |  |  | 1.2 (1.0–1.5) | Not significant | Yes | Yes | Lowest |
Jannz et al. (2012) [41] | Retrospective | In-hospital mortality | 79% | 61% | 2.53 (1.07–5.96) | Unfavorable | No | Yes | Highest |
Ihle et al. (2013) [46] | Retrospective | In-hospital mortality | 47% | 41% | 1.20 (0.51–2.82) | Not significant | Yes | Yes | Lowest |
Lee et al. (2014) [47] | Retrospective | In-hospital mortality |  |  | 0.60 (0.23–1.62) | Not significant | No | No |  |
Oh et al. (2014) [48] | Retrospective | In-hospital mortality | 63% | 52% | 1.03 (0.31–3.40) | Not significant | Yes | No | Defined timepoint |
Wang et al. (2014) [8] | Systematic review | In-hospital mortality |  |  | 1.40 (1.02–1.93) | Unfavorable | Yes |  |  |
Vaahersalo et al. (2014) [51] | Prospective | CPC at 12 months |  |  | 1.01 (0.998–1.01) | Not significant | No | Yes |  |
Helmerhorst et al. (2015) [42] | Retrospective | In-hospital mortality | 58% | 53% | 1.10 (0.95–1.27) | Not significant | Yes | Yes | Lowest |
Elmer et al. (2015) [43] | Retrospective | In-hospital mortality |  |  | 1.19 (1.02–1.39) | Unfavorable | Yes | Yes |  |
Elmer et al. (2015) [43] | Retrospective | In-hospital mortality |  |  | 0.99 (0.95–1.04) | Not significant | No | Yes |  |
Johnson et al. (2017) [44] | Retrospective | Neurological function at discharge |  |  | 5.88 (1.12–33.33) | Unfavorable* | Yes | Yes | Defined timepoint |
Auenmueller et al. (2017) [49] | Retrospective | Survival at 5 days |  |  | 0.85 (0.40–1.83) | Not significant |  | No | Defined timepoint |
Christ et al. (2017) [50] | Retrospective | In-hospital mortality | 46% | 66% | - | Favorable |  | No | Defined timepoint |
Patel et al. (2018) [52] | Systematic review | In-hospital mortality |  |  | 1.34 (1.08–1.67) | Unfavorable | Yes** |  |  |
Robert et al. (2018) [53] | Prospective | Neurological function at discharge | 59% | 52% | 1.25 (1.01–1.54) | Unfavorable | Yes | Yes | Defined timepoint |