Fig. 1From: Oxygen administration in patients recovering from cardiac arrest: a narrative reviewPathophysiology of hyperoxia. The redundant oxygen resulting from hyperoxia causes overproduction of ROS, which has pathophysiological consequences. ROS induces lipid peroxidation, protein oxidation, DNA damage, which result in neural cell dysfunction. Hyperoxia also causes cerebral vascular constriction, decreased cardiac output, and pulmonary dysfunction, which introduce reductions in oxygen delivery to the brainBack to article page