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Table 1 Patient characteristics and ventilator parameters on the day of admission

From: Prognosis of pathogen-proven acute respiratory distress syndrome diagnosed from a protocol that includes bronchoalveolar lavage: a retrospective observational study

  All patients (n = 70) Pathogen-proven ARDS group (n = 50) Pathogen-unproven ARDS group (n = 20) p
Age, year 66 (57–73) 67 (59–74) 60 (43–71) 0.097
Male 43 (61) 32 (64) 11 (55) 0.589
SOFA score 11 (9–13) 11 (9–13) 11 (10–13) 0.700
APACHE II score 29 (24–32) 29 (24–32) 28 (25–31) 0.745
Transferred from other hospital 26 (37) 21 (42) 5 (25) 0.274
Prior use of antibiotics 29 (41) 18 (36) 11 (55) 0.183
Comorbidities
 Heart failure 1 (1) 0 (0) 1 (5) 0.286
 Stroke 6 (9) 5 (10) 1 (5) 0.666
 COPD 7 (10) 4 (8) 3 (15) 0.399
 Renal failure 6 (9) 3 (6) 3 (15) 0.343
 Malignancy 16 (23) 13 (26) 3 (15) 0.529
 Liver failure 19 (27) 14 (28) 5 (25) 1.000
 Immunosuppression 17 (24) 11 (22) 6 (30) 0.543
Severity of ARDS (Berlin definition)     0.620
 Mild 10 (14) 6 (12) 4 (20)  
 Moderate 35 (47) 27 (50) 8 (40)  
 Severe 27 (39) 19 (38) 8 (40)  
Mechanical ventilation
 PaO2/FIO2 127 (85–179) 127 (82–176) 135 (96–196) 0.413
 FIO2 0.60 (0.40–0.76) 0.60 (0.45–0.80) 0.53 (0.40–0.74) 0.377
 PEEP 11 (8–14) 10 (8–14) 12 (10–14) 0.155
 Driving pressure 13 (10–16) 12 (10–14) 14 (10–16) 0.483
 TV 455 (389–529) 460 (397–524) 455 (364–550) 0.716
 TV/PBW 8.0 (7.0–9.4) 8.0 (7.0–10.0) 8.0 (7.1–9.2) 0.721
Septic shock 26 (37) 24 (48) 2 (10) 0.003
  1. Values are given as the median (interquartile range) or number (%). p values were calculated via Fisher’s exact test or the Mann-Whitney U test
  2. ARDS Acute respiratory distress syndrome, SOFA Sequential Organ Failure Assessment, APACHE Acute Physiology and Chronic Health Evaluation, COPD chronic obstructive pulmonary disease, PaO2 partial pressure of arterial oxygen, FIO2 fraction of inspiratory oxygen, PEEP positive end-expiratory pressure, TV tidal volume, PBW predicted body weight