Patients with HFNC success (n = 30) | Patients with HFNC failure (n = 16) | P value | AUROC | ||||
---|---|---|---|---|---|---|---|
Number of patients who remain on HFNC | HFNC success | Number of patients free of mechanical ventilation | HFNC failure | ||||
ROX index | Before initiation | 30 | 9.22 (7.61–12.46) | 16 | 10.30 (7.62–12.47) | 0.670 | 0.461 (0.286–0.637) |
1 h | 30 | 8.23 (6.58–11.44) | 15 | 6.55 (5.61–8.91) | 0.040 | 0.685 (0.522–0.849) | |
2 h | 30 | 8.73 (7.18–10.94) | 15 | 7.46 (6.17–9.40) | 0.177 | 0.626 (0.448–0.805) | |
4 h | 30 | 8.52 (6.67–962) | 15 | 7.20 (5.81–8.18) | 0.137 | 0.647 (0.472–0.821) | |
6 h | 28 | 8.86 (6.97–11.10) | 13 | 6.60 (5.62–8.00) | 0.015 | 0.754 (0.598–0.911) | |
8 h | 28 | 8.10 (7.12–11.79) | 12 | 7.52 (5.42–8.36) | 0.075 | 0.687 (0.514–0.860) | |
10 h | 28 | 9.06 (7.64–11.79) | 12 | 6.43 (5.42–8.51) | 0.010 | 0.773 (0.617–0.928) | |
12 h | 28 | 8.45 (7.70–10.27) | 12 | 6.55 (5.42–7.42) | 0.001 | 0.860 (0.728–0.992) | |
18 h | 25 | 9.60 (7.54–11.79) | 11 | 7.84 (5.71–9.78) | 0.137 | 0.665 (0.468–0.863) | |
24 h | 20 | 7.84 (6.68–10.62) | 10 | 5.93 (5.27–7.17) | 0.019 | 0.775 (0.561–0.990) | |
48 h | 12 | 5.82 (5.43–11.81) | 7 | 4.86 (3.88–7.92) | 0.128 | 0.764 (0.452–1.000) | |
Before termination* | NA | 12.12 (10.34–14.29) | NA | 5.17 (4.21–6.40) | < 0.001 | NA | |
Heart rate (beats/min) | Before initiation | 30 | 90 (74–99) | 16 | 93 (79–113) | 0.299 | 0.594 (0.419–0.769) |
1 h | 30 | 87 (77–95) | 15 | 94 (77–111) | 0.350 | 0.584 (0.397–0.771) | |
2 h | 30 | 82 (70–95) | 15 | 95 (84–106) | 0.039 | 0.693 (0.529–0.856) | |
4 h | 30 | 83 (72–100) | 15 | 94 (83–115) | 0.043 | 0.699 (0.518–0.881) | |
6 h | 28 | 81 (73–95) | 13 | 91 (82–110) | 0.182 | 0.640 (0.429–0.851) | |
8 h | 28 | 84 (68–96) | 12 | 90 (86–106) | 0.093 | 0.677 (0.497–0.856) | |
10 h | 28 | 83 (69–98) | 12 | 90 (82–115) | 0.084 | 0.682 (0.504–0.860) | |
12 h | 28 | 78 (70–94) | 12 | 95 (71–119) | 0.096 | 0.676 (0.464–0.889) | |
18 h | 25 | 80 (71–94) | 11 | 90 (78–112) | 0.142 | 0.663 (0.453–0.873) | |
24 h | 20 | 80 (73–100) | 10 | 80 (74–112) | 0.667 | 0.550 (0.320–0.781) | |
48 h | 12 | 74 (70–116) | 7 | 90 (74–103) | 0.574 | 0.575 (0.253–0.941) | |
Before termination* | NA | 80 (69–91) | NA | 104 (68–119) | 0.033 | NA | |
ROX-HR index | Before initiation | 30 | 11.54 (7.94–15.94) | 16 | 9.96 (9.05–14.90) | 0.549 | 0.554 (0.380–0.728) |
1 h | 30 | 9.14 (7.72–14.56) | 15 | 7.83 (5.90–10.98) | 0.045 | 0.681 (0.518–0.845) | |
2 h | 30 | 10.52 (8.62–13.76) | 15 | 8.70 (7.17–10.42) | 0.041 | 0.690 (0.532–0.849) | |
4 h | 30 | 9.47 (7.14–12.13) | 15 | 7.66 (5.05–10.48) | 0.050 | 0.692 (0.512–0.873) | |
6 h | 28 | 10.05 (7.93–13.94) | 13 | 6.87 (6.19–10.03) | 0.021 | 0.741 (0.572–0.909) | |
8 h | 28 | 10.91 (8.03–14.70) | 12 | 7.74 (5.42–9.30) | 0.028 | 0.731 (0.567–0.894) | |
10 h | 28 | 10.58 (9.00–15.11) | 12 | 7.22 (5.36–9.83) | 0.004 | 0.804 (0.660–0.948) | |
12 h | 28 | 12.00 (8.60–13.54) | 12 | 6.89 (5.98–7.41) | < 0.001 | 0.884 (0.738–1.000) | |
18 h | 25 | 11.10 (9.42–14.85) | 11 | 8.53 (6.18–10.62) | 0.034 | 0.735 (0.549–0.921) | |
24 h | 20 | 10.32 (7.48–13.45) | 10 | 6.77 (5.32–8.98) | 0.025 | 0.762 (0.547–0.977) | |
48 h | 12 | 7.89 (4.56–17.00) | 7 | 5.63 (4.699.30) | 0.423 | 0.639 (0.296–0.982) | |
Before termination* | NA | 15.79 (11.71–18.64) | NA | 5.23 (4.63–7.26) | < 0.001 | NA |