Table 1 Baseline characteristics of the included studies
From: Lymphopenia in severe coronavirus disease-2019 (COVID-19): systematic review and meta-analysis
Author | Study design | Country | Sample (n) | Gender (male %) | Age (years) | Cardiac comorbidity (%) | HT (%) | DM (%) |
|---|---|---|---|---|---|---|---|---|
Ruan et al. 2020 [7] | Retrospective | Wuhan, China | 150 | 102/150 (68%) | 67 non-survivor and 50 survivor (median) | 8.7 | 34.7 | 16.7 |
Yang et al. 2020 [6] | Retrospective | Wuhan, China | 52 | 35/52 (67%) | 59.7 (mean) | 9.6 | NR | 17.3 |
Zhou et al. 2020 [20] | Retrospective | Wuhan, China | 191 | 119/191 (62%) | 56 (median) | 7.9 | 30.4 | 18.8 |
Chen et al. 2020 [23] | Retrospective | Wuhan, China | 124 | 61/124 (49%) | 72 non-survivor and 53 survivor (median) | 16.1 | 33.1 | 11.3 |
Huang et al. 2020 [5] | Retrospective | Wuhan, China | 41 | 30/41 (73%) | 49 (median) | 14.6 | 14.6 | 19.5 |
Wang et al. 2020 [24] | Retrospective | Wuhan, China | 138 | 75/138 (54%) | 56 (median) | 14.5 | 31.2 | 10.1 |
Cao et al. 2020 [25] | Retrospective | Shanghai, China | 198 | 101/198 (51%) | 50.1 (mean) | 6.1 | 21.2 | 7.6 |
Wu et al. 2020 [26] | Retrospective | Wuhan, China | 201 | 30/41 (73%) | 51 (median) | 4.0 | 19.4 | 10.9 |
Yanli et al. 2020 [27] | Retrospective | Wuhan, China | 109 | 59/109 (54%) | 55 (median) | 6.4 | 33.9 | 11.0 |
Guan et al. 2020 [28] | Retrospective | Wuhan, China | 1099 | 640/1099 (58%) | 47 (median) | 2.5 | 15.0 | 7.4 |
Liu et al. 2020 [29] | Retrospective | Wuhan, China | 78 | 39 (58%) | 38 (median) | NR | 10.3 | 6.4 |
Zhang G et al 2020 [10] | Retrospective | Wuhan, China | 221 | 108/221 (48.9%) | 55 (median) | 10.0 | 24.4 | 10.0 |
Zhang et al. 2020 [11] | Retrospective | Wuhan, China | 140 | 71/140 (50.7%) | 57 (median) | 5.0 | 30.0 | 12.1 |
Wan et al. 2020 [12] | Retrospective | Chongqing, China | 135 | 72/135 (53.3%) | 47 (median) | 5.0 | 9.6 | 8.9 |
Qu et al. 2020 [13] | Retrospective | Huizhoi, China | 30 | 16/30 (53.3%) | 50.5 (median) | NR | NR | NR |
Qin et al. 2020 [14] | Retrospective | Wuhan, China | 452 | 235/ 452 (52%) | 58 (median) | 6.0 | 29.9 | 16.6 |
Wang et al. 2020 [15] | Retrospective | Wuhan, China | 110 | 48/110 (43%) | ≤ 40 (53%), 41–60 (21%), > 60 (36%) | 6.4 | 20.9 | 13.6 |
Feng et al. 2020 [16] | Retrospective | Wuhan, China | 141 | 72/141 (51.1%) | 44 (median) | 2.7 | 14.9 | 5.7 |
Lei et al. 2020 [17] | Retrospective | Chongqing, China | 51 | 32/51 (62.7%) | 45 (median) | NR | 7.8 | 7.8 |
Liu et al. 2020 [18] | Retrospective | Wuhan, China | 40 | 15/40 (37.5%) | 48.7 (mean) | NR | 15.0 | 15.0 |
Cai et al. 2020 [19] | Retrospective | Shenzhen, China | 298 | 149/298 (50%) | 47 (median) | NR | NR | NR |
Liu et al. 2020 [21] | Prospective | Beijing, China | 61 | 31/61 (50.8) | 40 (median) | 1.6 | 19.7 | 8.2 |
Tabata et al. 2020 [22] | Retrospective | Tokyo, Japan | 104 | 47/104 (45%) | 68 (median) | NR | NR | NR |