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Table 4 Multivariate logistic regression analysis of risk factors for 30-day mortality

From: Impact of host- and early treatment-related factors on mortality in ICU patients with candidemia: a bicentric retrospective observational study

VariablesModel 1Model 2
OR (95% CI)P valueOR (95% CI)P value
APACHE II score (1-point increments)1.14 (1.03–1.25)0.0071.14 (1.04–1.26)0.008
Renal replacement therapy*2.96 (0.91–9.61)0.0702.77 (0.87–8.80)0.085
Treatment ≤ 24 h following onset
 None or inappropriate antifungal therapy aloneReference   
 Appropriate antifungal therapy alone0.23 (0.02–3.12)0.267  
 CVC removal alone0.97 (0.29–3.29)0.961  
 Combined intervention1.66 (0.17–16.56)0.666  
Treatment ≤ 48 h following onset
 None or inappropriate antifungal therapy alone  Reference 
 Appropriate antifungal therapy alone  1.06 (0.17–6.50)0.948
 Source control alone  1.15 (0.30–4.43)0.840
 Combined therapy  0.59 (0.14–2.39)0.456
  1. APACHE acute physiology and chronic health evaluation, CI confidence interval, OR odds ratio
  2. *≤ 30 days before onset