| APACHE II score (1-point increments) | 1.14 (1.03–1.25) | 0.007 | 1.14 (1.04–1.26) | 0.008 |
| Renal replacement therapy* | 2.96 (0.91–9.61) | 0.070 | 2.77 (0.87–8.80) | 0.085 |
| Treatment ≤ 24 h following onset |
| None or inappropriate antifungal therapy alone | Reference | | | |
| Appropriate antifungal therapy alone | 0.23 (0.02–3.12) | 0.267 | | |
| CVC removal alone | 0.97 (0.29–3.29) | 0.961 | | |
| Combined intervention | 1.66 (0.17–16.56) | 0.666 | | |
| Treatment ≤ 48 h following onset |
| None or inappropriate antifungal therapy alone | | | Reference | |
| Appropriate antifungal therapy alone | | | 1.06 (0.17–6.50) | 0.948 |
| Source control alone | | | 1.15 (0.30–4.43) | 0.840 |
| Combined therapy | | | 0.59 (0.14–2.39) | 0.456 |
