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Table 1 Composition of the two hypertonic solutions compared in the trial

From: Low-chloride- versus high-chloride-containing hypertonic solution for the treatment of subarachnoid hemorrhage–related complications: The ACETatE (A low ChloriE hyperTonic solution for brain Edema) randomized trial

 

NaCl (standard treatment) group

NaCl/Na-acetate (alternate treatment) group

Solution components (per dose)

Sodium chloride

Sodium chloride and sodium acetate

Na Concentration [%]

23.4

16.4

NaCl pre-mixed solution, 4 mEq/ml [ml]

30

20

Na-acetate pre-mixed solution, 2 mEq/ml [ml]

0

30

Volume [ml]

30

50

Sodium content [mEq/dose]

120

140

Chloride content [mEq/dose]

120

80

Acetate content [mEq/dose]

0

60