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Table 2 Prevalence of clinical parameters among 2158 ED patients as reflected by the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of each parameter for sepsis (Sepsis-2). The pre-test probability of sepsis in this ED population was 17.8%

From: Monocyte distribution width enhances early sepsis detection in the emergency department beyond SIRS and qSOFA

Clinical parametersSepsis sensitivitySepsis specificitySepsis PPVSepsis NPV
Elevated MDW (> 20)74.0%72.0%36.5%92.7%
Abnormal WBC (< 4000 or > 12,000)68.8%81.6%44.8%92.3%
Tachycardia (HR > 90 bpm)74.5%67.7%33.4%92.4%
Elevated body temperature (< 96.8 °F or > 100.4 °F)20.0%98.7%77.0%85.0%
Tachypnea (RR > 20/min)20.3%93.0%38.6%84.3%
Hypotension (SBP ≤ 100 mmHg)15.8%97.1%54.0%84.2%
Altered mental status (GCS < 15)11.7%93.2%27.1%82.9%