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Table 2 Prevalence of clinical parameters among 2158 ED patients as reflected by the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of each parameter for sepsis (Sepsis-2). The pre-test probability of sepsis in this ED population was 17.8%

From: Monocyte distribution width enhances early sepsis detection in the emergency department beyond SIRS and qSOFA

Clinical parameters

Sepsis sensitivity

Sepsis specificity

Sepsis PPV

Sepsis NPV

Elevated MDW (> 20)

74.0%

72.0%

36.5%

92.7%

Abnormal WBC (< 4000 or > 12,000)

68.8%

81.6%

44.8%

92.3%

Tachycardia (HR > 90 bpm)

74.5%

67.7%

33.4%

92.4%

Elevated body temperature (< 96.8 °F or > 100.4 °F)

20.0%

98.7%

77.0%

85.0%

Tachypnea (RR > 20/min)

20.3%

93.0%

38.6%

84.3%

Hypotension (SBP ≤ 100 mmHg)

15.8%

97.1%

54.0%

84.2%

Altered mental status (GCS < 15)

11.7%

93.2%

27.1%

82.9%