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Table 4 Pharmacodynamic target of the time above the minimum inhibitory concentration

From: Clinical outcomes of empirical high-dose meropenem in critically ill patients with sepsis and septic shock: a randomized controlled trial

MIC (mg/L)

Standard-dose meropenem (n = 8)

High-dose meropenem (n = 10)

Identified MIC, n

3

5

• Achievement of 40%T>MIC, n (%)

3 (100%)

5 (100%)

• Achievement of 100%T>MIC, n (%)

2 (66.7%)

5 (100%)

MIC = 8, n

8

10

• Achievement of 40%T>MIC, n (%)

5 (62.5%)

9 (90%)

• Achievement of 100%T>MIC, n (%)

2 (25%)

4 (40%)

  1. MIC minimum inhibitory concentration, %T>MIC percent of the time of antibiotic concentrations above the minimum inhibitory concentration
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Journal of Intensive Care

ISSN: 2052-0492