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Table 2 Survival analysis assessing 28-day mortality, patient characteristics, and circadian rhythm parameters of the temperature

From: Circadian disruption of core body temperature in trauma patients: a single-center retrospective observational study

 UnivariateMultivariate
HR [95% CI]pHR [95% CI]p
Clinical variables
 Age1.04 [1.03–1.06]< 0.0011.06 [1.04–1.08]< 0.001
 Sex (male)1.73 [0.81–3.72]0.16  
 Body mass index0.91 [0.83–0.99]0.040.83 (0.75–0.93)< 0.001
 Glasgow Coma Scale0.90 [0.84–0.97]0.005  
 Traumatic brain injury2.05 [0.95–4.39]0.07  
 Intracranial hypertensiona5.70 [3.03–10.73]< 0.0015.60 [2.91–10.76]< 0.001
 Surgery at admission0.74 [0.41–1.33]0.32  
 ISS1.01 [0.99–1.03]0.26  
Temperature rhythm
 Period1.00 [0.98–1.02]0.65  
 Mesor0.42 [0.27–0.66]< 0.0010.62 [0.37–1.03]0.064
 Amplitude4.25 [1.58–11.41]0.0043.28 [1.15–9.30]0.026
  1. The analyses were performed using Cox regression model to estimate hazard ratios (HR) and their 95% confidence intervals (95% CIs)
  2. aGlasgow Coma Scale score not included in the multivariate analysis owing to collinearity with intracranial hypertension