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Table 2 The absolute change of sequential organ failure assessment score from the baseline

From: Dexmedetomidine improved renal function in patients with severe sepsis: an exploratory analysis of a randomized controlled trial

Data fieldDEX group (n = 54)Non-DEX group (n = 50)P value
Day 2, n (%)52 (96)48 (96) 
Respiratory subscore, median (IQR)0 (−1, 0)0(−1, 1)0.32
Cardiovascular subscore, median (IQR)0 (0, 0)0 (0, 0)0.38
Neurological subscore, median (IQR)0 (0, 1)0 (0, 1)0.87
Renal subscore, median (IQR)0 (−1, 0)0 (0, 0)0.08
Hepatic subscore, median (IQR)0 (0, 1)0 (0, 0)0.87
Coagulation subscore, median (IQR)1 (0, 1)0 (0, 1)0.32
Total SOFA score, median (IQR)a1 (−1, 2)1 (0, 3)0.20
Day 4, n (%)43 (80)41 (82) 
Respiratory subscore, median (IQR)0 (−1, 0)0 (−1, 1)0.11
Cardiovascular subscore, median (IQR)0 (−2, 0)0 (−2, 0)0.55
Neurological subscore, median (IQR)0 (−1, 0)0 (0, 0)0.22
Renal subscore, median (IQR)−1 (−1, 0)0 (−1, 0)0.02
Hepatic subscore, median (IQR)0 (0, 1)0 (0, 1)0.97
Coagulation subscore, median (IQR)1 (0, 2)1 (0, 2)0.89
Total score, median (IQR)− 1 (−3, 2)0 (−3, 3)0.19
Day 6, n (%)33 (61)32 (64) 
Respiratory subscore, median (IQR)0 (−2, 1)0 (−1, 0)0.93
Cardiovascular subscore, median (IQR)− 1 (− 3, 0)0 (−3, 0)0.52
Neurological subscore, median (IQR)0 (− 1, 0)0 (0, 0)0.37
Renal subscore, median (IQR)− 1 (−1, 0)− 1 (−1, 0)0.23
Hepatic subscore, median (IQR)0 (0, 1)0 (0, 1)0.91
Coagulation subscore, median (IQR)1 (0, 2)1 (0, 2)0.78
Total score, median (IQR)− 2 (−4, 2)− 2 (−5, 1)0.78
  1. DEX dexmedetomidine, SOFA sequential organ failure assessment, IQR interquartile range
  2. aThe SOFA score ranges from 0 to 24, with higher scores indicating more severe disease. The SOFA score consists of six organ-subscores ranges from 0 to 4