Table 1 Patient characteristics in the included trials
Authors | Year | Target population | Number of patients | Sex (male) | Age | Physiological severity |
|---|---|---|---|---|---|---|
I/C | I/C | I/C | I/C | |||
Patman [14] | 2001 | Adult patients who underwent cardiac surgery in SICU | 101/109 | 81/77 | 62.8 (12.2)/67.3 (14.4) | -/- |
Schweickert [15] | 2009 | Sedated adult patients with MV in the ICU | 49/55 | 20/22 | 57.7 (36.3-69.1)/54.4 (46.5-66.4) | 20 (15.8-24.0)/19 (13.3-23.0)* |
Brummel [16] | 2014 | Adult patients with respiratory failure and/or shock in ICU | 22/22 | 13/8 | 62 (48-67)/60 (51-69) | 21.5 (20.0-28.8)/27 (17.5-31.0) * |
Kayambu [17] | 2015 | Critically ill adult patients admitted to ICU with sepsis | 26/24 | 18/14 | 62.5 (30-83)/65.5 (37-85) | 28 (7.6)/27 (6.8) * |
Morris [18] | 2016 | Adult patients admitted to the ICU with MV | 150/150 | 66/68 | 55 (17)/58 (14) | 76 (26)/75 (27) †|
Moss [19] | 2016 | Adult patients who required MV | 59/61 | 36/35 | 56 (14)/49 (15) | 17.9 (6.2)/17.4 (5.6) * |
Schaller [20] | 2016 | Adult patients with MV in SICU | 104/96 | 65/61 | 66 (48-73)/64 (45-76) | 16 (12-22)/17 (11-22) * |
Dong Z [21] | 2016 | Adult patients who underwent CABG | 53/53 | 20/22 | 62.6 (12.8)/60.2 (15.1) | 16.3 (4.2)/17.2 (4.3) * |
Hodgson [22] | 2016 | Critically ill adult patients with MV in ICU | 29/21 | 21/9 | 64 (12)/53 (15) | 19.8 (9.8)/15.9 (6.9) * |
Maffei [23] | 2017 | Liver transplant recipients in ICU | 20/20 | 15/16 | 54 (9)/52 (9) | 43 (14)/45 (12) ‡ |
Moradian [24] | 2017 | Adult patients who underwent CABG | 49/49 | 33/30 | 59 (10)/60 (11.3) | -/- |