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Table 3 Pharmacokinetic parameters

From: Enhanced renal clearance and impact on vancomycin pharmacokinetic parameters in patients with hemorrhagic stroke

VariablePredicted value
(n = 17)
Calculated value
(n = 17)
p value
Creatinine clearance (mL/min), mean ± SD116.7 ± 10.3161.6 ± 16.70.001
Elimination rate constant (h−1), mean ± SD0.087 ± 0.010.141 ± 0.020.004
Half-life (h), mean ± SD8.7 ± 0.66.5 ± 0.90.03
Volume of distribution (L), mean ± SD57.6 ± 2.671.8 ± 11.30.23