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Table 1 Patients’ characteristics

From: A comprehensive protocol for ventilator weaning and extubation: a prospective observational study

 

All patients

PERF

Non-PERF

p values

(n = 248)

(n = 24)

(n = 224)

Age (years)

65 ± 17

64 ± 18

65 ± 17

0.8

Women, n (%)

77 (31)

7 (29)

70 (31)

1.0

APACHE II score just before extubation

13 (10–16)

12.5 (11–16)

13 (10–16)

0.8

SOFAT score just before extubation

5 (4–6)

5 (4–6.3)

5 (4–6)

0.5

RSBI (breaths/min/L)

44 ± 21

45 ± 18

44 ± 21

0.9

Duration of mechanical ventilation (days)

7 (5–11)

7.5 (5–13.3)

7 (5–11)

0.6

Reason for mechanical ventilation, n (%)

   

0.2

 ARDS

159 (64.1)

14 (58)

145 (65)

 

 Congestive heart failure

57 (23.0)

5 (21)

52 (23)

 

 Post-cardiac arrest syndrome

30 (12.1)

4 (16)

26 (12)

 

 COPD exacerbation

2 (0.8)

1 (4)

1 (0.4)

 

Comorbid diseases, n (%)

   

0.4

 COPD

17 (7)

5 (21)

12 (5)

 

 Coronary artery disease

35 (14)

5 (21)

30 (13)

 

 Chronic heart failure

25 (10)

4 (17)

21 (9)

 

 Chronic renal failure

14 (6)

1 (4)

13 (6)

 

 Diabetes mellitus

44 (18)

8 (33)

36 (16)

 

 Hypertension

85 (34)

9 (38)

76 (34)

 

Vital signs just before extubation

 Heart rate (beats/min)

88 ± 19

88 ± 19

88 ± 18

0.9

 MAP (mmHg)

90 ± 15

89 ± 16

90 ± 15

0.6

 RR (breaths/min)

20 ± 7

20 ± 6

20 ± 7

0.9

ABG values just before extubation

 pH

7.45 ± 0.04

7.45 ± 0.04

7.45 ± 0.04

0.5

 PaCO2 (mmHg)

38 ± 6

39 ± 5

38 ± 6

0.5

 PaO2/FiO2

301 ± 83

282 ± 88

303 ± 83

0.3

  1. Data are presented as mean ± standard deviation, median and interquartile range, or number (percentage). PERF post-extubation respiratory failure, APACHE II Acute Physiology and Chronic Health Evaluation II, SOFAT score sequential organ failure assessment score under tracheal intubation, RSBI rapid shallow breathing index, ARDS acute respiratory distress syndrome, COPD chronic obstructive pulmonary disease, MAP mean arterial pressure, RR respiratory rate, ABG arterial blood gas, PaCO2 partial pressure of carbon dioxide, PaO2 partial pressure of arterial oxygen, FiO2 fraction of inspired oxygen