Table 3 Results of mixed-model analysis with SOFA score as main outcome
Variables | Daily SOFA score | Delta SOFA | Coefficients | p value | ||||
|---|---|---|---|---|---|---|---|---|
Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | ||||
Fluid overload status | ||||||||
 Yes (n = 47) | 9.30 (2.53) | 8.83 (2.69) | 7.98 (3.60) | 7.41 (3.72) | 7.13 (3.69) | 2.15 (3.50) | 1.16 | 0.014 |
 No (n = 73) | 8.85 (2.84) | 7.91 (3.20) | 5.95 (3.06) | 4.72 (3.14) | 4.30 (3.12) | 4.52 (3.74) |  | |
Baseline SOFA score | ||||||||
 < 8 (n = 60) | 7.53 (1.88) | 7.09 (2.52) | 6.16 (2.79) | 5.19 (3.21) | 4.54 (3.14) | 2.04 (3.28) | 2.50 | < 0.001 |
 > 8 (n = 68) | 10.52 (2.61) | 9.40 (3.10) | 7.53 (3.83) | 6.64 (3.95) | 6.36 (3.91) | 4.92 (4.14) | ||
Cardiovascular disease | ||||||||
 Yes (n = 65) | 8.92 (2.86) | 7.98 (3.01) | 6.15 (3.45) | 5.09 (3.77) | 4.61 (3.68) | 4.53 (4.44) | − 0.60 | 0.183 |
 No (n = 61) | 9.25 (2.62) | 8.49 (3.10) | 7.45 (3.33) | 6.65 (3.43) | 6.20 (3.52) | 2.63 (3.37) |  | |