Variable | Intervention group | Control group | p value |
---|---|---|---|
Positive SF | Positive BC | ||
N = 19 | N = 25 | ||
Appropriate empirical antimicrobial therapy | 13 (76.5%) | 18 (75.0%) | 1.000** |
Antimicrobial de-escalation after SF or BC results, n (%) | 17 (89.5%) | 21 (84.0%) | 0.700** |
Antimicrobial re-escalation ≤ 7 days by clinical worsening, n (%) | 2 (10.5%) | 7 (28.0%) | 0.300** |
Time to antimicrobial therapy adjustment (h), median (IQR) | 8 (7–14) | 54 (38–75) | < 0.001* |
Duration of antimicrobial therapy (days), mean (SD) | 12 ± 5 | 15 ± 4 | 0.039*** |