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Table 4 Antimicrobial management in patients during the study in patients with positive tests

From: The effect of a rapid molecular blood test on the use of antibiotics for nosocomial sepsis: a randomized clinical trial

Variable

Intervention group

Control group

p value

Positive SF

Positive BC

N = 19

N = 25

Appropriate empirical antimicrobial therapy

13 (76.5%)

18 (75.0%)

1.000**

Antimicrobial de-escalation after SF or BC results, n (%)

17 (89.5%)

21 (84.0%)

0.700**

Antimicrobial re-escalation ≤ 7 days by clinical worsening, n (%)

2 (10.5%)

7 (28.0%)

0.300**

Time to antimicrobial therapy adjustment (h), median (IQR)

8 (7–14)

54 (38–75)

< 0.001*

Duration of antimicrobial therapy (days), mean (SD)

12 ± 5

15 ± 4

0.039***

  1. *Mann–Whitney test, **Fisher’s exact test, ***T test