Skip to main content

Table 4 Antimicrobial management in patients during the study in patients with positive tests

From: The effect of a rapid molecular blood test on the use of antibiotics for nosocomial sepsis: a randomized clinical trial

Variable Intervention group Control group p value
Positive SF Positive BC
N = 19 N = 25
Appropriate empirical antimicrobial therapy 13 (76.5%) 18 (75.0%) 1.000**
Antimicrobial de-escalation after SF or BC results, n (%) 17 (89.5%) 21 (84.0%) 0.700**
Antimicrobial re-escalation ≤ 7 days by clinical worsening, n (%) 2 (10.5%) 7 (28.0%) 0.300**
Time to antimicrobial therapy adjustment (h), median (IQR) 8 (7–14) 54 (38–75) < 0.001*
Duration of antimicrobial therapy (days), mean (SD) 12 ± 5 15 ± 4 0.039***
  1. *Mann–Whitney test, **Fisher’s exact test, ***T test