Fig. 3

Sensitivity analyses for potential confounders. Primary analysis was further adjusted for each potential confounder. Odds ratios greater than 1.0 indicate an increased risk of death. The models were adjusted as follows: primary analysis for age, sex, and Sequential Organ Failure Assessment (SOFA) score; model 1 for age, sex, SOFA score, and Charlson Comorbidity Index; model 2 for age, sex, SOFA score, and admission category (medical or surgical); model 3 for age, sex, SOFA score, Charlson Comorbidity Index, and admission category; model 4 for age, sex, and Acute Physiology and Chronic Health Evaluation (APACHE) II score; model 5 for age, sex, and Simplified Acute Physiology Score (SAPS) II; and model 6 for age, sex, and SOFA score using generalized estimating equations (GEE) with each source of infection. Estimates are shown as mean differences with 95% confidence intervals