|
Characteristics
|
All patients (n = 75)
|
Infection group (n = 27)
|
Sepsis group (n = 48))
|
P value
|
|---|
|
Sex, no. (%)
|
|
Mena
|
51
|
(68.0)
|
19
|
(70.3)
|
32
|
(66.7)
|
0.741
|
|
Womena
|
24
|
(32.0)
|
8
|
(29.6)
|
16
|
(33.3)
|
|
Age (years)
|
77
|
(63–84)
|
69
|
(57–78)
|
81
|
(65.5–84.5)
|
0.016
|
|
SBP (mmHg)
|
130
|
(115–147)
|
132
|
(122–146)
|
129
|
(105–150)
|
0.540
|
|
RR (breaths/min)
|
24
|
(19–30)
|
24
|
(20–26)
|
25
|
(18–30)
|
0.268
|
|
HR (beats/min)
|
105
|
(91–120)
|
96
|
(84–108)
|
109.5
|
(96–128)
|
0.006
|
|
GCS< 15, no.(%)a
|
37
|
(49.3)
|
3
|
(11.1)
|
34
|
(70.8)
|
< 0.001
|
|
BT (°C)
|
37.9
|
(36.8–38.9)
|
37.8
|
(36.7–38.4)
|
37.9
|
(37.1–39.2)
|
0.279
|
|
SpO2 (%)
|
96
|
(93–98)
|
96
|
(94–98)
|
95
|
(91.5–97)
|
0.034
|
|
Site of infection, no. (%)
|
|
Respiratorya
|
35
|
(46.7)
|
8
|
(29.6)
|
27
|
(56.2)
|
0.027
|
|
Urinarya
|
14
|
(18.6)
|
5
|
(18.5)
|
9
|
(18.7)
|
0.980
|
|
Abdominala
|
19
|
(25.3)
|
10
|
(37.0)
|
9
|
(18.7)
|
0.080
|
|
Cutaneousa
|
5
|
(6.7)
|
4
|
(14.8)
|
1
|
(2.0)
|
0.034
|
|
Neurologicala
|
1
|
(1.3)
|
0
|
0.0
|
1
|
(2.0)
|
0.450
|
|
Bone and jointsa
|
1
|
(1.3)
|
0
|
0.0
|
1
|
(2.0)
|
0.450
|
|
Othersa
|
0
|
0.0
|
0
|
0.0
|
0
|
0.0
|
–
|
|
Organ dysfunction (SOFA)
|
|
Respiratory systema
|
40
|
(53.3)
|
5
|
(18.5)
|
35
|
(72.9)
|
< 0.001
|
|
Coagulation
|
18
|
(24.0)
|
0
|
0.0
|
18
|
(37.5)
|
< 0.001
|
|
Hepatic system
|
26
|
(34.6)
|
6
|
(22.2)
|
20
|
(41.6)
|
0.089
|
|
Cardiovascular system
|
10
|
(13.3)
|
0
|
0.0
|
10
|
(20.8)
|
0.011
|
|
Cental nervous system
|
37
|
(49.3)
|
3
|
(11.1)
|
34
|
(70.8)
|
< 0.001
|
|
Renal system
|
22
|
(29.3)
|
1
|
(3.7)
|
21
|
(43.7)
|
< 0.001
|
|
Laboratory results
|
|
WBC (/μL)
|
11,350
|
(8800–14,300)
|
12,510
|
(9620–17,500)
|
11,030
|
(8595–13,325)
|
0.294
|
|
Creatinine (mg/dL)
|
0.92
|
(0.74–1.28)
|
0.81
|
(0.73–0.92)
|
0.99
|
(0.77–1.62)
|
0.006
|
|
Bilirubin (mg/dL)
|
0.9
|
(0.6–1.4)
|
0.7
|
(0.5–1.1)
|
1.05
|
(0.6–1.75)
|
0.067
|
|
Platelets (103/μL)
|
19.4
|
(13.5–23.4)
|
21.4
|
(18.4–25.5)
|
18.4
|
(10.8–22.2)
|
0.009
|
|
Lactate (mmol/L)
|
1.8
|
(1.24–2.68)
|
1.4
|
(1.1–1.6)
|
1.99
|
(1.51–3.07)
|
< 0.001
|
|
Q-CRT (s)
|
3.143
|
(2.009–5.868)
|
2.207
|
(1.591–3.269)
|
3.923
|
(2.529–6.694)
|
< 0.001
|
|
Q-CRT > 3.5, no.(%)a
|
33
|
(44.0)
|
5
|
(18.5)
|
28
|
(58.3)
|
0.001
|
| SIRS ≧ 2, no.(%) |
55
|
(73.3)
|
16
|
(59.2)
|
39
|
(81.2)
|
0.039
|
| qSOFA ≧ 2, no. (%) |
32
|
(42.6)
|
0
|
0.0
|
32
|
(66.7)
|
< 0.001
|
- Infection group infected patients without organ dysfunction. Sepsis group (including septic shock) infected patients with organ dysfunction. SBP systolic blood pressure, RR respiratory rate, HR heart rate, GCS Glasgow Coma Scale score, BT body temperature, SpO2 hemoglobin saturation, WBC white blood cell count, Q-CRT quantitative capillary refill time, SIRS systemic inflammatory response syndrome, qSOFA quick sequential organ failure assessment. aFrequency (%); other values: median (IQR)
