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Table 3 Correlation analysis between serum suPAR and neutrophilic uPAR with other laboratory and clinical parameters markers in ICU patients

From: Neutrophils are a main source of circulating suPAR predicting outcome in critical illness

Parameter suPAR (serum) uPAR (neutrophils)
r p r p
Inflammation
 C-reactive protein 0.232 0.015 − 0.264 0.007
 Procalcitonin 0.422 < 0.001 − 0.329 0.001
 WBC 0.169 0.059 − 0.227 0.017
 Interleukin-6 0.506 < 0.001 − 0.345 0.001
 TNF 0.253 0.009 − 0.24 0.013
 Interleukin-10 0.248 0.012 − 0.24 0.014
Renal function
 Creatinine 0.512 < 0.001 − 0.342 0.001
 GFR (creatinine) − 0.511 < 0.001 0.289 0.003
 Urea 0.469 < 0.001 − 0.271 0.006
Liver function
 AST 0.3 0.003 − 0.214 0.028
 ALT 0.159 0.075 − 0.121 0.137
 Bilirubin 0.5 < 0.001 − 0.238 0.014
 Albumin − 0.24 0.019 0.204 0.04
 Gamma GT 0.227 0.02 − 0.19 0.043
 Alkaline phosphatase 0.246 0.018 − 0.231 0.025
Clinical course
 Days in hospital 0.301 0.009 − 0.093 0.238
 Days at ICU 0.21 0.027 − 0.03 0.391
  1. Abbreviations: ALT/AST alanine/aspartate aminotransferase, GFR glomerular filtration rate, ICU intensive care unit, TNF tumor necrosis factor, (s)uPAR (soluble) urokinase plasminogen activation receptor, WBC white blood cell count
  2. Spearman rank correlation test, significant correlations (p < 0.05) highlighted in italics