Table 3 Multivariate logistic regression of HDL-S1P, SA-S1P, S1P carrier proteins (HDL and SA), and various other inflammatory markers as predictors for sepsis severity defined as septic shock or SOFA score ≥ 8
Variable | Regression coefficient | Odds ratio (95% CI) | Significance (P value) |
|---|---|---|---|
HDL-S1P, μg/L | − 0.146 | 0.86 (0.77–0.97) | < 0.05 |
SA-S1P, μg/L | + 0.070 | 1.07 (0.94–1.23) | ns |
HDL, mg/dL | − 0.320 | 0.73 (0.55–0.97) | < 0.05 |
SA, g/L | + 0.166 | 1.18 (0.85–1.64) | ns |
Leucocytes, ×109/L | + 0.105 | 1.11 (0.96–1.29) | ns |
CRP, mg/L | + 0.000 | 1.00 (0.98–1.02) | ns |
Interleukin-6, ng/L | + 0.001 | 1.00 (1.00–1.00) | ns |
Procalcitonin, μg/L | + 0.254 | 1.29 (0.87–1.91) | ns |