Physician agreement on the diagnosis of sepsis in the intensive care unit: estimation of concordance and analysis of underlying factors in a multicenter cohort

Table 5 Test for the ability of clinical parameters to distinguish between SIRS patients who did or did not receive therapeutic antibiotics

Parameter	Number of datapoints available¹		p value
Parameter	Patients receiving antibiotics	Patients not receiving antibiotics	p value
MAP.Min	75	52	0.003
HR.Max	78	52	0.007
Temp.Max	78	52	0.011
Hospital LoS	78	52	0.014
N.SIRS	78	52	0.022
SOFA	54	36	0.043
Log₂ PCT	51	34	0.054
APACHE	78	51	0.080
WBC.Min	78	51	0.153
pH	34	17	0.183
Age	78	52	0.272
Race: non-white	23/78 (29.5%)	20/52 (38.5%)	0.286
Race: white	55/78 (70.5%)	32/52 (61.5%)	0.286
WBC.Max	78	51	0.352
Glucose.Max	68	46	0.406
SeptiScore	78	52	0.413
Sex: female	35/78 (44.9%)	27/52 (51.9%)	0.430
Sex: male	43/78 (55.1%)	25/52 (48.1%)	0.430
Lactate	39	17	0.473
MAP.Max	58	42	0.694
ICU LoS	78	52	0.749
Temp.Min	74	51	0.760
HR.Min	78	52	0.960

Diagnosis of SIRS (N = 130) was by consensus RPD. Parameters are listed on the basis of decreasing significance (two-tailed p value) as evaluated either by t test (for continuous variables) or by a two-proportions z-test (www.vassarstats.net) for categorical variables
Abbreviations: Glucose.Max maximum blood glucose concentration, HR.Max maximum heart rate, HR.Min minimum heart rate, ICU LoS length of stay in ICU (days), MAP.Max maximum mean arterial blood pressure, MAP.Min minimum mean arterial blood pressure, N.SIRS number of SIRS criteria met, Temp.Max maximum core temperature, Temp.Min minimum core temperature, WBC.Max maximum white blood cell count, WBC.Min minimum white blood cell count
¹No imputation of missing values was performed

ISSN: 2052-0492