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Table 4 Parameters that vary significantly between different infection site subgroups

From: Physician agreement on the diagnosis of sepsis in the intensive care unit: estimation of concordance and analysis of underlying factors in a multicenter cohort

Parameter Mean ± SD (non-respiratory) Mean ± SD (respiratory) p value1
Number in group 48 49  
Overall agreement 0.85 ± 0.05 0.62 ± 0.08 6.0E-09
Free-marginal κ 0.77 ± 0.07 0.43 ± 0.12 6.8E-09
No. of indeterminates (identified by discharge consensus assessment) 6/48 = 12.5% 15/49 = 30.6% 0.030
Lowest MAP 53.9 ± 16.4 64.4 ± 17.1 0.003
Max temperature 38.3 ± 1.0 37.7 ± 0.8 0.002
Min temperature 36.0 ± 0.70 36.4 ± 0.7 0.03
Log2 PCT 2.58 ± 3.10 − 0.46 ± 3.82 0.001
  1. Patients with identified sites of infection (N = 97) were stratified into the following subgroups: non-respiratory (abdominal + urinary + other; N = 48) and respiratory (pneumonia + non-pneumonia; N = 49). Parameters that varied significantly (p < 0.05) between these two groups were identified by statistical testing (t test for continuous parameters; two-proportions z-test for categorical parameters)
  2. 1Two-tailed t test for all parameters except for overall agreement and number of indeterminates, for which a two-proportion z-test was run instead (www.vassarstats.net)