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Table 3 Analysis of Reclassification Events

From: Physician agreement on the diagnosis of sepsis in the intensive care unit: estimation of concordance and analysis of underlying factors in a multicenter cohort

Reclassification Number (%) reclassified: attending physician ➔ discharge evaluation by site investigators (Additional file 3: Figure S3–1) Number (%) reclassified: attending physician ➔ RPD (Additional file 3: Figure S3–2) Change in apparent in risk profile Potential consequence of erroneous initial classification
SIRS to sepsis 4 (1.6%) 6 (2.4%) Low to high Delayed antibiotic treatment, prolonged hospital stay, and increased morbidity and mortality
Indeterminate to sepsis 12 (4.8%) 22 (8.8%) Medium to high Possible delayed antibiotic treatment
SIRS to indeterminate 5 (2.0%) 5 (2.0%) Low to medium Possible delayed antibiotic treatment
Sepsis to SIRS 9 (3.6%) 9 (3.6%) High to low Excess antibiotic use
Indeterminate to SIRS 18 (7.2%) 16 (6.4%) Medium to low Possible excess antibiotic use
Sepsis to indeterminate 15 (6.0%) 12 (4.8%) High to medium Possible excess antibiotic use
Total 63 (25.3%) 70 (28.1%)