|
Time from cannulation to ECMO started (min), median (IQR)
|
15 (6.5–32.5)
|
16 (15–52)
|
15 (6–32)
|
0.37
|
|
Duration of ECMO (days)
|
3 (1–4)
|
3 (1–4)
|
3 (2–5)
|
0.65
|
|
Length of mechanical ventilation (days)
|
10 (6–16)
|
11 (7–23)
|
8 (5–14)
|
0.21
|
|
Length of ICU stay (days)
|
16 (9–23)
|
18 (9–30)
|
16 (8–20)
|
0.17
|
|
Length of hospital stay (days)
|
51 (25–76)
|
55 (27–125)
|
51 (22–70)
|
0.30
|
|
Before ECMO, median (IQR)
|
|
PH
|
7.22 (7.05–7.38)
|
7.19 (7.03–7.44)
|
7.23 (7.07–7.36)
|
0.86
|
|
PaCO2 (mmHg)
|
38 (48–68)
|
47 (40–87)
|
49 (37–66)
|
0.39
|
|
PaO2 (mmHg)
|
103 (55–169)
|
85 (41–121)
|
122 (75–246)
|
0.13
|
|
HCO3 (cmH2O)
|
21 (15–26)
|
22 (15–28)
|
20 (15–25)
|
0.28
|
|
Lactate (mmol/L)
|
9.9 (4.1–14.15)
|
7.7 (3.4–15.5)
|
10.5 (5.3–13.8)
|
0.88
|
|
FiO2
|
0.6 (0.5–1.0)
|
0.8 (0.6–1.0)
|
0.6 (0.50–1.00)
|
0.57
|
|
PEEP (cmH2O)
|
8 (5–10)
|
9 (6–10)
|
8 (4–10)
|
0.74
|
|
On-ECMO 6 h, median (IQR)
|
|
PH
|
7.42 (7.34–7.50)
|
7.44 (7.35–7.51)
|
7.41 (7.33–7.49)
|
0.47
|
|
PaCO2 (mmHg)
|
32 (27–39)
|
31 (25–36)
|
33 (27–40)
|
0.36
|
|
PaO2 (mmHg)
|
322 (148–470)
|
239 (113–430)
|
367 (186–490)
|
0.047
|
|
HCO3 (cmH2O)
|
21 (18–24)
|
20 (16–26)
|
22 (18–24)
|
0.71
|
|
Lactate (mmol/L)
|
5.8 (4.4–9.1)
|
5.9 (4.7–8.7)
|
5.8 (3.4–9.8)
|
0.74
|
|
FiO2
|
0.5 (0.4–0.6)
|
0.6 (0.5–0.7)
|
0.5 (0.4–0.6)
|
0.38
|
|
PEEP (cmH2O)
|
8 (5–10)
|
7 (5–8)
|
8 (5–10)
|
0.01
|
|
ACT (seconds)
|
187 (165–207)
|
201 (168–214)
|
185 (160–202)
|
0.23
|
|
ECMO blood flow (L/min)
|
2.2 (1.9–2.8)
|
2.2 (2.0–3.0)
|
2.2 (1.8–2.6)
|
0.36
|
|
On-ECMO 24 h, median IQR
|
|
PaO2/FiO2
|
462 (264–672)
|
438 (208–598)
|
469 (299–740)
|
0.18
|
|
PH
|
7.43 (7.38–7.52)
|
7.44 (7.38–7.55)
|
7.42 (7.37–7.51)
|
0.26
|
|
PaCO2 (mmHg)
|
36 (29–40)
|
33 (27–39)
|
36 (30–42)
|
0.30
|
|
PaO2 (mmHg)
|
221 (133–322)
|
210 (125–274)
|
246 (136–350)
|
0.28
|
|
HCO3 (cmH2O)
|
24 (22–27)
|
25 (19–29)
|
24 (22–27)
|
0.62
|
|
Lactate (mmol/L)
|
2.8 (1.9–4.4)
|
3.2 (2.8–4.9)
|
2.6 (1.3–4.4)
|
0.19
|
|
FiO2
|
0.4 (0.4–0.6)
|
0.5 (0.4–0.6)
|
0.4 (0.4–0.5)
|
0.08
|
|
PEEP (cmH2O)
|
8 (6–10)
|
8 (5–10)
|
8 (7–10)
|
0.57
|
|
ACT (seconds)
|
182 (161–196)
|
182 (160–196)
|
186 (163–197)
|
0.54
|
|
ECMO blood flow (L/min)
|
2.2 (1.7–3.0)
|
2.3 (1.9–3.0)
|
2.2 (1.7–3.1)
|
0.63
|
|
Lactate clearance, median (IQR)
|
|
At 6 h (%)
|
15 (−27 to 54)
|
4 (−51 to 57)
|
18 (−17 to 54)
|
0.59
|
|
At 24 h (%)
|
61 (18 to 80)
|
51 (−20 to 83)
|
61 (18 to 80)
|
0.71
|
