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Table 3 Comparison of clinical outcome and laboratory data between the pre-ECMO team and post-ECMO team established

From: Establishing extracorporeal membrane oxygenation team increased number of patients and improved data recording

  All patients (n = 69) Pre-ECMO team (n = 27) Post-ECMO team (n = 42) p value
Time from cannulation to ECMO started (min), median (IQR) 15 (6.5–32.5) 16 (15–52) 15 (6–32) 0.37
Duration of ECMO (days) 3 (1–4) 3 (1–4) 3 (2–5) 0.65
Length of mechanical ventilation (days) 10 (6–16) 11 (7–23) 8 (5–14) 0.21
Length of ICU stay (days) 16 (9–23) 18 (9–30) 16 (8–20) 0.17
Length of hospital stay (days) 51 (25–76) 55 (27–125) 51 (22–70) 0.30
Before ECMO, median (IQR)
 PH 7.22 (7.05–7.38) 7.19 (7.03–7.44) 7.23 (7.07–7.36) 0.86
 PaCO2 (mmHg) 38 (48–68) 47 (40–87) 49 (37–66) 0.39
 PaO2 (mmHg) 103 (55–169) 85 (41–121) 122 (75–246) 0.13
 HCO3 (cmH2O) 21 (15–26) 22 (15–28) 20 (15–25) 0.28
 Lactate (mmol/L) 9.9 (4.1–14.15) 7.7 (3.4–15.5) 10.5 (5.3–13.8) 0.88
 FiO2 0.6 (0.5–1.0) 0.8 (0.6–1.0) 0.6 (0.50–1.00) 0.57
 PEEP (cmH2O) 8 (5–10) 9 (6–10) 8 (4–10) 0.74
On-ECMO 6 h, median (IQR)
 PH 7.42 (7.34–7.50) 7.44 (7.35–7.51) 7.41 (7.33–7.49) 0.47
 PaCO2 (mmHg) 32 (27–39) 31 (25–36) 33 (27–40) 0.36
 PaO2 (mmHg) 322 (148–470) 239 (113–430) 367 (186–490) 0.047
 HCO3 (cmH2O) 21 (18–24) 20 (16–26) 22 (18–24) 0.71
 Lactate (mmol/L) 5.8 (4.4–9.1) 5.9 (4.7–8.7) 5.8 (3.4–9.8) 0.74
 FiO2 0.5 (0.4–0.6) 0.6 (0.5–0.7) 0.5 (0.4–0.6) 0.38
 PEEP (cmH2O) 8 (5–10) 7 (5–8) 8 (5–10) 0.01
 ACT (seconds) 187 (165–207) 201 (168–214) 185 (160–202) 0.23
 ECMO blood flow (L/min) 2.2 (1.9–2.8) 2.2 (2.0–3.0) 2.2 (1.8–2.6) 0.36
On-ECMO 24 h, median IQR
 PaO2/FiO2 462 (264–672) 438 (208–598) 469 (299–740) 0.18
 PH 7.43 (7.38–7.52) 7.44 (7.38–7.55) 7.42 (7.37–7.51) 0.26
 PaCO2 (mmHg) 36 (29–40) 33 (27–39) 36 (30–42) 0.30
 PaO2 (mmHg) 221 (133–322) 210 (125–274) 246 (136–350) 0.28
 HCO3 (cmH2O) 24 (22–27) 25 (19–29) 24 (22–27) 0.62
 Lactate (mmol/L) 2.8 (1.9–4.4) 3.2 (2.8–4.9) 2.6 (1.3–4.4) 0.19
 FiO2 0.4 (0.4–0.6) 0.5 (0.4–0.6) 0.4 (0.4–0.5) 0.08
 PEEP (cmH2O) 8 (6–10) 8 (5–10) 8 (7–10) 0.57
 ACT (seconds) 182 (161–196) 182 (160–196) 186 (163–197) 0.54
 ECMO blood flow (L/min) 2.2 (1.7–3.0) 2.3 (1.9–3.0) 2.2 (1.7–3.1) 0.63
Lactate clearance, median (IQR)
 At 6 h (%) 15 (−27 to 54) 4 (−51 to 57) 18 (−17 to 54) 0.59
 At 24 h (%) 61 (18 to 80) 51 (−20 to 83) 61 (18 to 80) 0.71
  1. ECMO extracorporeal membrane oxygenation, IQR interquartile range, PEEP positive end-expiratory pressure, ACT activated clotting time