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Table 2 Results of the generalized linear mixed model analysis in which patient volume was included as a continuous variable

From: Volume-outcome relationship on survival and cost benefits in severe burn injury: a retrospective analysis of a Japanese nationwide administrative database

Population of severe burn patients adjusted by the prognostic burn index

 Primary outcome

N (%)

Crude odds ratio (95% CI)

p value

Adjusted odds ratio (95% CI)

p value

  In-hospital mortality

1287 (24.5)

1.07 (1.05–1.09)

< 0.001

1.14 (1.09–1.19)

< 0.001

 Secondary outcomes

Median [IQR]

Crude difference (95% CI)

p value

Adjusted difference (95% CI)

p value

  Total healthcare costs per admission, USD

23,628 [7452, 58,458]

3278 (3043–3512)

< 0.001

4876 (4436–5316)

< 0.001

  Hospital-free days at 90 days, days

28 [0, 67]

− 1.6 (− 1.7 to − 1.5)

< 0.001

− 3.1 (− 3.4 to − 2.8)

< 0.001

Population who were directly transported from the scene of injury adjusted by the prognostic burn index

 Primary outcome

N (%)

Crude odds ratio (95% CI)

p value

Adjusted odds ratio (95% CI)

p value

  In-hospital mortality

1017 (27.3)

1.14 (1.11–1.18)

< 0.001

1.22 (1.17–1.30)

< 0.001

 Secondary outcomes

Median [IQR]

Crude difference (95% CI)

p value

Adjusted difference (95% CI)

p value

  Total healthcare costs per admission, USD

22,723 [7087, 58,753]

6191 (5703–6678)

< 0.001

6755 (6076–7434)

< 0.001

  Hospital-free days at 90 days, days

22 [0, 66]

− 3.0 (− 3.2 to − 2.7)

< 0.001

− 4.4 (− 4.9 to − 3.9)

< 0.001

Population whose prognostic burn index ≤ 120 adjusted by the prognostic burn index

 Primary outcome

N (%)

Crude odds ratio (95% CI)

p value

Adjusted odds ratio (95% CI)

p value

  In-hospital mortality

876 (18.4)

1.07 (1.05–1.09)

< 0.001

1.16 (1.10–1.22)

< 0.001

 Secondary outcomes

Median [IQR]

Crude difference (95% CI)

p value

Adjusted difference (95% CI)

p value

  Total healthcare costs per admission, USD

25,289 [8356, 59,223]

3823 (3544–4101)

< 0.001

6021 (5501–6541)

< 0.001

  Hospital-free days at 90 days, days

36 [0, 69]

− 1.7 (− 1.9 to − 1.6)

< 0.001

− 3.5 (− 3.8 to − 3.2)

< 0.001

Cohort of severe burn patients who survived for more than 2 days of admission adjusted by the developed risk adjustment model

 Primary outcome

N (%)

Crude odds ratio (95% CI)

p value

Adjusted odds ratio (95% CI)

p value

  In-hospital mortality

956 (19.4)

1.07 (1.05–1.09)

< 0.001

1.04 (0.98–1.10)

0.174

 Secondary outcomes

Median [IQR]

Crude difference (95% CI)

p value

Adjusted difference (95% CI)

p value

  Total healthcare costs per admission, USD

26,832 [9224, 62,428]

3871 (3604–4138)

< 0.001

6689 (5892–7487)

< 0.001

  Hospital-free days at 90 days, days

35 [0, 68]

− 1.7 (− 1.8 to − 1.6)

< 0.001

− 2.1 (− 2.4 to − 1.8)

< 0.001

  1. Patient severity was also adjusted by the hospital unique identifier as a random effect variable. IQR interquartile range, CI confidence interval, USD US dollars