Table 1 Comparisons of total intravenous fluid and vasopressor use of researches by Rivers et al. in 2001, and the ProCESS, ARISE, and ProMISe in 2014 to 2015
From: Aggressive fluid management in the critically ill: Pro
Total intravenous fluid (mL) | Vasopressors use (%) | |||||||
|---|---|---|---|---|---|---|---|---|
Baseline (pre-randomization) | 0–6 h | 6–72 h | 0–72 h | Baseline (pre-randomization) | 0–6 h | 6–72 h | 0–72 h | |
Rivers E, et al (2001) [3] | ||||||||
Standard therapy (n = 133) | – | 3499 ± 2438 | 10,602 ± 6216 | 13,358 ± 7729 | – | 30.3 | 42.9 | 51.3 |
EGDT (n = 130) | – | 4981 ± 2984 | 8625 ± 5162 | 13,443 ± 6390 | – | 27.4 | 29.1 | 36.8 |
ProCESS (2014) [4] | ||||||||
Protocol-based EGDT (n = 439) | 2245 ± 1472 | 2805 ± 1957 | 4458 ± 3878 | 7253 ± 4605 | 19.1 | 54.9 | 47.6 | 60.4 |
Protocol-based standard (n = 446) | 2226 ± 1363 | 3285 ± 1743 | 4918 ± 4308 | 8193 ± 4989 | 16.8 | 52.2 | 46.6 | 61.2 |
Usual care (n = 456) | 2083 ± 1405 | 2279 ± 1881 | 4354 ± 3882 | 6633 ± 4560 | 15.1 | 44.1 | 43.2 | 53.7 |
ARISE (2014) [5] | ||||||||
EGDT (n = 793) | 2515 ± 1244 | 1964 ± 1415 | 4274 ± 3071 | – | 21.8 | 66.6 | 58.8 | – |
Usual care (n = 798) | 2519 ± 1331 | 1713 ± 1401 | 4382 ± 3136 | – | 21.7 | 57.8 | 51.5 | – |
ProMISe (2015) [6] | ||||||||
EGDT (n = 625) | 1890 ± 1105 | 2226 ± 1443 | 4215 ± 3068 | 5946 ± 3740 | 2.4 | 53.3 | 57.9 | 60.5 |
Usual resuscitation (n = 626) | 1965 ± 1149 | 2022 ± 1271 | 4366 ± 3114 | 5844 ± 3651 | 3.4 | 46.6 | 52.6 | 55.0 |