Skip to main content

Advertisement

Table 2 Comparison of assessment for fluid boluses and fluid responsiveness between cardiac and standard monitored patients

From: Calibrated cardiac output monitoring versus standard care for fluid management in the shocked ICU patient: a pilot randomised controlled trial

Variable Total Standard Cardiac monitor p value
Fluid boluses
 Average number of boluses (n)* 1 (0.4) 1 (0.4) 2 (0.5) 0.237
 Total fluid given as boluses (ml)* 500 (0–1200) 500 (0–1250) 500 (0–1130) 0.234
Reason for giving fluid bolus#
 Number of fluid boluses 114    
 Hypotension (n) 52 (46) 32 (58) 20 (35) 0.015
 Urine output (n) 15 (13) 11 (20) 4 (7) 0.055
 Tachycardia (n) 8 (7) 5 (9) 3 (5) 0.486
 Lactate (n) 15 (13) 14 (25) 1 (2) 0.001
 Clinical exam findings (n) 2 (2) 2 (4) 0 0.239
 Increasing noradrenaline requirement 36 (31) 12 (21) 24 (41) 0.022
 TTE assessment 16 (14) 10 (18) 6 (10) 0.248
 SVV, CI, CO, EVLW or GEDV 25 (22) 0 25 (43) 0.001
 Passive leg raise 4 (4) 3 (5) 1 (2) 0.360
Assessment of response to fluid
 No assessment of response to fluid (n) 49 (43) 25 (45) 24 (41) 0.725
 Urine output (n) 6 (5) 2 (4) 4 (7) 0.427
 Change in MAP (n) 24 (21) 19 (34) 5 (9) 0.001
 Change in NR requirements (n) 32 (28) 11 (20) 21 (36) 0.049
 SVV, CI, CO, EVLW or GEDV 15 (13) 0 15 (26) 0.001
  1. Results for normal distributed data given as frequency (percentage)
  2. *Non-normally distributed data presented as median (25th centile, 75th centile). TTE transthoracic echocardiogram, SVV stroke volume variation, CI cardiac index, CO cardiac output, EVLW extra-vascular lung water, GEDV global end-diastolic volume
  3. #Clinicians may have recorded multiple reasons for each bolus, each reason has been scored. Italicised p values indicated significant difference between the two groups