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Table 2 Comparison of assessment for fluid boluses and fluid responsiveness between cardiac and standard monitored patients

From: Calibrated cardiac output monitoring versus standard care for fluid management in the shocked ICU patient: a pilot randomised controlled trial

Variable

Total

Standard

Cardiac monitor

p value

Fluid boluses

 Average number of boluses (n)*

1 (0.4)

1 (0.4)

2 (0.5)

0.237

 Total fluid given as boluses (ml)*

500 (0–1200)

500 (0–1250)

500 (0–1130)

0.234

Reason for giving fluid bolus#

 Number of fluid boluses

114

   

 Hypotension (n)

52 (46)

32 (58)

20 (35)

0.015

 Urine output (n)

15 (13)

11 (20)

4 (7)

0.055

 Tachycardia (n)

8 (7)

5 (9)

3 (5)

0.486

 Lactate (n)

15 (13)

14 (25)

1 (2)

0.001

 Clinical exam findings (n)

2 (2)

2 (4)

0

0.239

 Increasing noradrenaline requirement

36 (31)

12 (21)

24 (41)

0.022

 TTE assessment

16 (14)

10 (18)

6 (10)

0.248

 SVV, CI, CO, EVLW or GEDV

25 (22)

0

25 (43)

0.001

 Passive leg raise

4 (4)

3 (5)

1 (2)

0.360

Assessment of response to fluid

 No assessment of response to fluid (n)

49 (43)

25 (45)

24 (41)

0.725

 Urine output (n)

6 (5)

2 (4)

4 (7)

0.427

 Change in MAP (n)

24 (21)

19 (34)

5 (9)

0.001

 Change in NR requirements (n)

32 (28)

11 (20)

21 (36)

0.049

 SVV, CI, CO, EVLW or GEDV

15 (13)

0

15 (26)

0.001

  1. Results for normal distributed data given as frequency (percentage)
  2. *Non-normally distributed data presented as median (25th centile, 75th centile). TTE transthoracic echocardiogram, SVV stroke volume variation, CI cardiac index, CO cardiac output, EVLW extra-vascular lung water, GEDV global end-diastolic volume
  3. #Clinicians may have recorded multiple reasons for each bolus, each reason has been scored. Italicised p values indicated significant difference between the two groups