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Table 3 Decline in thigh muscle thickness and outcome

From: Trends of loss of peripheral muscle thickness on ultrasonography and its relationship with outcomes among patients with sepsis

Muscle thickness Day1 Day3 Day5 Day7
a. In-hospital mortality
 Survivors (n) 59 59 53 28
  Muscle thickness (mean ± SD) 31.3 ± 8.5 30.2 ± 8.3 29.6 ± 8.0 30.4 ± 7.4
  % Decline [median (IQR)] NA 2.6(1.4,5.1) 3.7(2.8, 8.3) 4.8(3.6, 9.8)
 Non-Survivors (n) 11 11 10 7
  Muscle thickness (mean ± SD) 30.9 ± 9.4 28.5 ± 9.0 27.6 ± 8.7 26.4 ± 8.7
  % Decline [median (IQR)] NA 7.5(5.2, 11.4) 13.0(10.0, 15.7) 15.5(10.4, 17.8)
p value (% decline) NA < 0.001 < 0.001 < 0.003
b. ICU-acquired weakness
 Absent (n) 55 55 48 23
  Muscle thickness (mean ± SD) 31.5 ± 8.1 30.3 ± 7.8 29.9 ± 7.2 29.9 ± 6.8
  % Decline [median (IQR)] NA 2.9 (1.6, 5.2) 3.7 (2.9, 9.1) 5.1 (3.3, 10.4)
 Present (n) 15 15 15 12
  Muscle thickness (mean ± SD) 30.2 ± 10.3 28.5 ± 10.4 27.3 ± 10.4 28.9 ± 9.5
  % Decline [median (IQR)] NA 5.7 (2.9, 8.4) 9.9 (5.5, 13.0) 11.0 (6.5, 16.8)
p value (% decline) NA 0.04 0.02 0.02
c. 90-days outcome
 Stable outcome (n) 42 42 36 17
  Muscle thickness (mean ± SD) 31.7 ± 7.9 31.0 ± 7.7 30.9 ± 7.0 31.6 ± 6.6
  % Decline [median (IQR)] NA 2.1 (− 5.0, 7.9) 3.1 (− 2.0, 9.6) 4.2 (− 2.6, 9.1)
 Poor outcome (n) 17 17 17 11
  Muscle thickness (mean ± SD) 30.1 ± 9.9 28.2 ± 9.6 26.8 ± 9.3 28.5 ± 8.6
  % Decline [median (IQR)] NA 5.7 (0.8, 14.4) 9.9 (3.5, 26.9) 10.9 (2.7, 33.7)
p value (% decline) NA < 0.0001 < 0.0001 0.0003