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Table 6 Blood gas analysis during the SBT

From: Clinical evidence for respiratory insufficiency type II predicts weaning failure in long-term ventilated, tracheotomised patients: a retrospective analysis

Factor Weaning success
n = 60
Weaning failure
n = 64
OR [95% KI] p value
PaCO2 > 45 mmHg at admission, n (%)
 No 35 (53%) 31 (47%) 1 0.23
 Yes 24 (42%) 33 (58%) 0.64 [0.32, 1.32]  
 Missing 1 0   
PaCO2 prior to the first SBT (mmHg)
 Mean ± SD 40 ± 7 45 ± 14 0.61 [0.41, 0.93] 0.021
 Median (IQR) 40 (36–43) 44 (36–54)   
 Min–max 18–59 23–115   
 Missing 1 1   
PaCO2 > 45 mmHg prior to the first SBT, n (%)
 No 50 (56%) 39 (44%) 1 0.006
 Yes 9 (27%) 24 (73%) 0.29 [0.12, 0.70]  
PaCO2 after the first SBT (mmHg)
 Mean ± SD 45 ± 9 55 ± 12 0.40 [0.26, 0.62] < 0.0001
 Median (IQR) 43 (39–48) 54 (47–63)   
 Min–max 32–81 29–89   
 Missing 2 10   
pH values after the first SBT
 Mean ± SD 7.46 ± 0.05 7.41 ± 0.09 3.23 [1.66, 6.31] 0.0006
 Median (IQR) 7.46 (7.44–7.49) 7.42 (7.36–7.46)   
 Min–max 7.36–7.56 7.19–7.67   
 Missing 3 10   
pH values prior to the first SBT
 Mean ± SD 7.50  ± 0.06 7.49 ± 0.09 1.15 [0.71, 1.86] 0.58
 Median (IQR) 7.49 (7.46–7.54) 7.49 (7.42–7.56)   
 Min–max 7.40–7.68 7.26–7.68   
 Missing 1 1   
PaO2 prior to the first SBT (mmHg)
 Mean ± SD 74 ± 19 80 ± 30 0.91 [0.78, 1.06] 0.22
 Median (IQR) 75 (61–87) 72 (60–97)   
 Min–max 34–115 37–169   
 Missing 3 5   
PaO2 values at the end of the first SBT
 Mean ± SD 71 ± 24 85 ± 41 0.88 [0.77, 1.00] 0.056
 Median (IQR) 65 (52–79) 70 (62–97)   
 Min–max 42–139 32–231   
 Missing 6 13   
  1. Data are expressed as n % according to the underlying weaning subgroup), mean ± SD (min–max), median (IQR) as well as missing data (missing)
  2. IQR interquartile range, max maximum value, min minimal value, PaCO2 arterial partial pressure of carbon dioxide, PaO2 arterial partial pressure of oxygen, SD standard deviation