Table 1 Serum drug concentration levels of (nor)fluoxetoine and (9-OH)risperidone during hospital admission
From: Late presentation of Torsades de Pointes related to fluoxetine following a multiple drug overdose
Hours after hospital admission | Fluoxetine (ref 100–450 mcg/l) | Norfluoxetine (ref 50–350 mcg/l) | Sum (ref 15–500 mcg/l) | Risperidone (ref 4–30 mcg/l) | 9-OH-risperidone (ref 12–60 mcg/l) | Sum (ref 20–60 mcg/l) |
|---|---|---|---|---|---|---|
T = 0 | 2700 | 397 | 3097 | 33 | 4 | 37 |
T + 1.33 | 2300 | 370 | 2670 | 36 | 3 | 39 |
T + 16.3 | 1550 | 310 | 1860 | 13 | 6 | 19 |
T + 36.9 | 1650 | 281 | 1931 | 7 | 5 | 12 |
T + 70.0 | 1120 | 263 | 1383 | 2 | 4 | 6 |
T + 88.5 | 990 | 300 | 1290 | NA | NA | NA |