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Table 1 Baseline characteristics

From: Hepcidin predicts response to IV iron therapy in patients admitted to the intensive care unit: a nested cohort study

Characteristic*

Outcome (n = 133)

Age—years

62 (41–73)

Male gender—no. (%)

91 (68)

ICU admission source—no (%)

 Emergency department

24 (18)

 Hospital ward

8 (6)

 Operating theater

97 (73)

 Other hospital

4 (3)

ICU admission type—no (%)

 Medical

17 (13)

 General surgical

20 (15)

 Cardiothoracic

49 (37)

 Trauma

42 (32)

 Neurosurgical

5 (4)

APACHE II score

12 (9–17)

SOFA score

6 (4–9)

Prior RBC transfusion—no (%)

30 (23)

Haemoglobin—g/L

88 (81–94)

Mean corpuscular volume—fL

91 (88–94)

C reactive protein—mg/L

110 (48–170)

Iron—mcg/dL

3 (2–6)

Ferritin—ng/ml+

260 (161–437)

Transferrin—mg/dL

17 (15–20)

Transferrin saturation—%

9 (6–16)

Soluble transferrin receptor—mg/L

1.81 (1.28–2.44)

Hepcidin—μg/mL

34.9 (17.3–69.2)

 Tertile 1—(0–20.08)

10.6 (4.2–15.6)

 Tertile 2—(20.09–53.00)

34.9 (27.1–48.5)

 Tertile 3—(53.01–163.46)

81.2 (69.2–97.9)

  1. ICU intensive care unit, APACHE acute physiology and chronic health evaluation, SOFA sequential organ failure assessment, RBC red blood cell
  2. *Median and interquartile range (IQR) unless otherwise reported
  3. +ng/ml has a conversion factor of 1 to the standard international units mcg/ml