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Table 1 Baseline characteristics

From: Hepcidin predicts response to IV iron therapy in patients admitted to the intensive care unit: a nested cohort study

Characteristic* Outcome (n = 133)
Age—years 62 (41–73)
Male gender—no. (%) 91 (68)
ICU admission source—no (%)
 Emergency department 24 (18)
 Hospital ward 8 (6)
 Operating theater 97 (73)
 Other hospital 4 (3)
ICU admission type—no (%)
 Medical 17 (13)
 General surgical 20 (15)
 Cardiothoracic 49 (37)
 Trauma 42 (32)
 Neurosurgical 5 (4)
APACHE II score 12 (9–17)
SOFA score 6 (4–9)
Prior RBC transfusion—no (%) 30 (23)
Haemoglobin—g/L 88 (81–94)
Mean corpuscular volume—fL 91 (88–94)
C reactive protein—mg/L 110 (48–170)
Iron—mcg/dL 3 (2–6)
Ferritin—ng/ml+ 260 (161–437)
Transferrin—mg/dL 17 (15–20)
Transferrin saturation—% 9 (6–16)
Soluble transferrin receptor—mg/L 1.81 (1.28–2.44)
Hepcidin—μg/mL 34.9 (17.3–69.2)
 Tertile 1—(0–20.08) 10.6 (4.2–15.6)
 Tertile 2—(20.09–53.00) 34.9 (27.1–48.5)
 Tertile 3—(53.01–163.46) 81.2 (69.2–97.9)
  1. ICU intensive care unit, APACHE acute physiology and chronic health evaluation, SOFA sequential organ failure assessment, RBC red blood cell
  2. *Median and interquartile range (IQR) unless otherwise reported
  3. +ng/ml has a conversion factor of 1 to the standard international units mcg/ml