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Table 3 Univariate and multiple logistic regressions for having ECMO instituted in the first 48-h post-operative cardiac surgery

From: Predictors and outcomes of early post-operative veno-arterial extracorporeal membrane oxygenation following infant cardiac surgery

Variables Univariate OR (95% CI) p value Multiple regression model 1a OR (95% CI) p value Multiple regression model 2a OR (95% CI) p value
Highest vasoactive-inotrope score day 1 1.05 (1.03, 1.07) < 0.001 1.04 (1.02, 1.06) < 0.001   
Highest vasoactive-inotrope score > 30 day 1 13.44 (4.76, 33) < 0.001    12.1 (4.25, 34.4) < 0.001
Highest lactate day 1 (mmol/L) 1.30 (1.16, 1.46) < 0.001 1.2 (1.06, 1.35) 0.003   
Highest lactate day 1 > 6 mmol/L 4.76 (1.85, 12.5) 0.001    3.45 (1.34, 8.91) 0.010
Lowest base deficit day 1 0.80 (0.70, 0.90) < 0.001 0.82 (0.71, 0.94) 0.004 0.80 (0.70, 0.91) 0.001
Single-ventricle anatomy 3.83 (1.50, 9.76) 0.005 5.35 (1.66, 17.31) 0.005 3.88 (1.35, 11.15) 0.012
Open sternum from operating-room 7.85 (1.81, 34.17) 0.006     
Highest epinephrine dose day 1 (0.1 μg/kg/min) 13.44 (4.86, 37.15) 0.008     
Cardiopulmonary bypass time (minutes) 1.01 (1.00, 1.02) 0.010 1.01 (1.00, 1.02) 0.002 1.01 (1.00, 1.02) 0.020
Highest creatinine day 1 (μmol/L) 1.03 (1.01, 1.05) 0.010     
Post-operative dialysis 8.54 (1.66, 44.03) 0.010     
Lowest pH day 1 (0.1 unit) 0.00 (0.00, 0.00) 0.010     
Deep hypothermic circulatory arrest time (minutes) 1.03 (1.01, 1.06) 0.010     
Need to re-institute cardiopulmonary bypass 3.72 (1.30, 10.62) 0.014     
Aortic cross-clamp time (minutes) 1.01 (1.00, 1.03) 0.100     
  1. Data are given as odds ratio (OR) and 95% confidence interval (95% CI)
  2. aTwo multiple regressions are shown: with inotrope score and lactate as continuous measures (model 1) and with inotrope score and lactate as dichotomous measures (model 2). Dialysis is not used in multiple regressions, as too few patients had dialysis