Advertisement
Table 3 Univariate and multiple logistic regressions for having ECMO instituted in the first 48-h post-operative cardiac surgery
| Variables | Univariate OR (95% CI) | p value | Multiple regression model 1a OR (95% CI) | p value | Multiple regression model 2a OR (95% CI) | p value |
|---|---|---|---|---|---|---|
| Highest vasoactive-inotrope score day 1 | 1.05 (1.03, 1.07) | < 0.001 | 1.04 (1.02, 1.06) | < 0.001 | ||
| Highest vasoactive-inotrope score > 30 day 1 | 13.44 (4.76, 33) | < 0.001 | 12.1 (4.25, 34.4) | < 0.001 | ||
| Highest lactate day 1 (mmol/L) | 1.30 (1.16, 1.46) | < 0.001 | 1.2 (1.06, 1.35) | 0.003 | ||
| Highest lactate day 1 > 6 mmol/L | 4.76 (1.85, 12.5) | 0.001 | 3.45 (1.34, 8.91) | 0.010 | ||
| Lowest base deficit day 1 | 0.80 (0.70, 0.90) | < 0.001 | 0.82 (0.71, 0.94) | 0.004 | 0.80 (0.70, 0.91) | 0.001 |
| Single-ventricle anatomy | 3.83 (1.50, 9.76) | 0.005 | 5.35 (1.66, 17.31) | 0.005 | 3.88 (1.35, 11.15) | 0.012 |
| Open sternum from operating-room | 7.85 (1.81, 34.17) | 0.006 | ||||
| Highest epinephrine dose day 1 (0.1 μg/kg/min) | 13.44 (4.86, 37.15) | 0.008 | ||||
| Cardiopulmonary bypass time (minutes) | 1.01 (1.00, 1.02) | 0.010 | 1.01 (1.00, 1.02) | 0.002 | 1.01 (1.00, 1.02) | 0.020 |
| Highest creatinine day 1 (μmol/L) | 1.03 (1.01, 1.05) | 0.010 | ||||
| Post-operative dialysis | 8.54 (1.66, 44.03) | 0.010 | ||||
| Lowest pH day 1 (0.1 unit) | 0.00 (0.00, 0.00) | 0.010 | ||||
| Deep hypothermic circulatory arrest time (minutes) | 1.03 (1.01, 1.06) | 0.010 | ||||
| Need to re-institute cardiopulmonary bypass | 3.72 (1.30, 10.62) | 0.014 | ||||
| Aortic cross-clamp time (minutes) | 1.01 (1.00, 1.03) | 0.100 |
