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Table 2 Process and clinical outcomes

From: Echocardiogram-guided resuscitation versus early goal-directed therapy in the treatment of septic shock: a randomized, controlled, feasibility trial

Process outcomes

ECHO (n = 15)

EGDT (n = 15)

p value

 Time from sepsis identification to ICU admission (min)

56

82

0.42

 Time from sepsis identification to randomization (h)

3.1

4

0.33

 Fluid administration prior to study protocol (median L, median ml/kg)

3, 33

3, 38

0.53

 Fluid administration during study protocol (median L [IQR, range])

0 (0, 2, range 0–7)

1 (0, 2, range 0–6)

0.61

 24 h fluid administrationa (L, median, IQR)

6 (4.7, 8.5)

6.4 (4.8, 9.6)

0.63

 Dobutamine administered (n, %)

3 (20)

2 (13)

> 0.99

 Patients receiving ≤ 1 L of fluid during study protocol (n, %)

11 (73)

11 (73)

> 0.99

Clinical outcomes

 Change in SOFA score at 48 h (median, IQR)

− 4 (+ 4 to − 10)

− 6 (− 4 to − 12)

0.10

 28-day mortality (n, %)

5 (33)

3 (20)

0.68

 ICU-free days (median, IQR)

24.2 (0, 25.8)

24.5 (5.4, 25.8)

0.97

 Ventilator-free days (median, IQR)

28 (0, 28)

25 (9, 28)

0.51