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Table 9 Outcomes in smokers, former smokers, and never smokers with severe sepsis or septic shock due to pneumonia (N = 241)

From: The impact of smoking on patient outcomes in severe sepsis and septic shock

Outcomes Current smokers (N = 53) Non-smokers (N = 188) P value* Former smokers (N = 116) P value** Never smokers (N = 72) P value§
Mortalityn (%) 18 (34) 45 (24) 0.14 33 (28) 0.47 12 (17) 0.03
Hospital LOS—median days (IQR) 8 (5–20) 7 (4–12) 0.13 7.5 (4–13) 0.16 7 (5–12) 0.20
Hospital LOS in survivors 10 (5–21) 7 (4–12) 0.02 7 (4–13) 0.03 7 (5–12) 0.05
ICU LOS 7 (3–13) 6 (3–12) 0.70 6 (3–11) 0.77 6 (2–12) 0.68
ICU LOS survivors 8 (4–13) 5 (2–12) 0.14 4 (2–11) 0.14 6 (3–12) 0.28
Required ICU admission—n (%) 41 (77) 104 (55) < 0.01 66 (57) 0.01 38 (53) < 0.01
Required vasopressors—n (%) 33 (62) 72 (38) < 0.01 48 (41) 0.01 24 (33) < 0.01
Vasopressor days—median (IQR) 3 (2–5) 3 (2–6) 0.73 3 (2–6) 0.62 3 (2–5) 0.97
Required mechanical ventilation—n (%) 39 (74) 66 (35) < 0.01 42 (36) < 0.01 24 (33) < 0.01
Ventilator days 5 (3–12) 6 (3–10) 0.78 6 (3–11) 0.60 4 (3–8) 0.85
Required dialysis—n (%) 6 (11) 15 (8) 0.45 10 (9) 0.58 5 (7) 0.39
Dialysis days 4.5 (3–10) 6 (2–14) 0.70 10 (4–14) 0.32 2 (2–2) 0.52
  1. LOS length of stay, ICU intensive care unit
  2. *P value refers to comparison between current smokers and non-smokers
  3. **P value refers to comparison between current smokers and former smokers
  4. §P value refers to comparison between current smokers and never smokers
  5. Includes death or discharge to hospice