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Table 8 Multivariable analysis of active smoking and requiring mechanical ventilation in severe sepsis and septic shock (current smokers vs. non-smokers)

From: The impact of smoking on patient outcomes in severe sepsis and septic shock

Risk factor Odds ratio (95% CI) P value
Current smoking 2.38 (1.06–5.34) 0.04
Alcohol abuse 0.99 (0.37–2.66) 0.99
72 h fluid balance 1.05 (0.97–1.11) 0.21
Age 0.98 (0.96–1.01) 0.21
Charlson score 0.92 (0.78–1.09) 0.33
SOFA 1.53 (1.37–1.70) < 0.01
COPD 1.13 (0.52–2.43) 0.76
Hospital acquired sepsis 1.25 (0.45–3.45) 0.66
Severe sepsis 0.45 (0.23–0.88) 0.02
Genitourinary infect 0.26 (0.12–0.55) < 0.01
Abdominal 0.40 (0.18–0.88) 0.02
Soft tissue 0.31 (0.10–0.96) 0.04
Medical ICU admission 0.13 (0.05–0.33) < 0.01