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Table 8 Multivariable analysis of active smoking and requiring mechanical ventilation in severe sepsis and septic shock (current smokers vs. non-smokers)

From: The impact of smoking on patient outcomes in severe sepsis and septic shock

Risk factor

Odds ratio (95% CI)

P value

Current smoking

2.38 (1.06–5.34)

0.04

Alcohol abuse

0.99 (0.37–2.66)

0.99

72 h fluid balance

1.05 (0.97–1.11)

0.21

Age

0.98 (0.96–1.01)

0.21

Charlson score

0.92 (0.78–1.09)

0.33

SOFA

1.53 (1.37–1.70)

< 0.01

COPD

1.13 (0.52–2.43)

0.76

Hospital acquired sepsis

1.25 (0.45–3.45)

0.66

Severe sepsis

0.45 (0.23–0.88)

0.02

Genitourinary infect

0.26 (0.12–0.55)

< 0.01

Abdominal

0.40 (0.18–0.88)

0.02

Soft tissue

0.31 (0.10–0.96)

0.04

Medical ICU admission

0.13 (0.05–0.33)

< 0.01