Table 1 Patient characteristics
From: Serial change of C1 inhibitor in patients with sepsis: a prospective observational study
| Characteristic | Non-shock | Non-refractory shock | Refractory shock | p |
|---|---|---|---|---|
| N | 14 | 13 | 13 | |
| Age (± SD) (years) | 66.8 ± 17.1 | 72.5 ± 10.4 | 71.0 ± 12.2 | 0.5346 |
| Male (%) | 11 (78.6) | 9 (69.2) | 10 (76.9) | 0.8388 |
| Survivor n (%) | 14 (100) | 13 (100) | 3 (23.1) | < .0001 |
| APACHE II score | 13.1 ± 5.9 | 25.5 ± 5.7 | 27.9 ± 10.2 | < .0001 |
| SOFA score | 4.3 ± 0.9 | 9.4 ± 0.9 | 9.7 ± 0.9 | 0.0001 |
| Volume of infusion over the first 48 h after admission (± SD) (mL) | 9735.5 ± 6852.9 | 11,765.2 ± 6369.4 | 18,390.7 ± 8908.8 | 0.0127 |
| Mean volume of infusion/h over the first 48 h after admission (± SD) (mL/h) | 204.3 ± 140.6 | 263.9 ± 146.2 | 484.0 ± 146.3 | < .0001 |
| Diagnosis (n) | ||||
| Pneumonia | 1 | 3 | 3 | |
| Urinary tract infection | 2 | 2 | 3 | |
| Gas gangrene | 3 | 1 | 2 | |
| Abdominal infection | 3 | 5 | 2 | |
| CNS infection | 1 | 1 | 0 | |
| Infective endocarditis | 1 | 0 | 0 | |
| Cellulitis | 1 | 1 | 3 | |
| Others | 2 | 0 | 0 | |