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Table 1 Patient characteristics

From: Serial change of C1 inhibitor in patients with sepsis: a prospective observational study

Characteristic Non-shock Non-refractory shock Refractory shock p
N 14 13 13  
Age (± SD) (years) 66.8 ± 17.1 72.5 ± 10.4 71.0 ± 12.2 0.5346
Male (%) 11 (78.6) 9 (69.2) 10 (76.9) 0.8388
Survivor n (%) 14 (100) 13 (100) 3 (23.1) < .0001
APACHE II score 13.1 ± 5.9 25.5 ± 5.7 27.9 ± 10.2 < .0001
SOFA score 4.3 ± 0.9 9.4 ± 0.9 9.7 ± 0.9 0.0001
Volume of infusion over the first 48 h after admission (± SD) (mL) 9735.5 ± 6852.9 11,765.2 ± 6369.4 18,390.7 ± 8908.8 0.0127
Mean volume of infusion/h over the first 48 h after admission (± SD) (mL/h) 204.3 ± 140.6 263.9 ± 146.2 484.0 ± 146.3 < .0001
Diagnosis (n)
 Pneumonia 1 3 3
 Urinary tract infection 2 2 3
 Gas gangrene 3 1 2
 Abdominal infection 3 5 2
 CNS infection 1 1 0
 Infective endocarditis 1 0 0
 Cellulitis 1 1 3
 Others 2 0 0
  1. APACHE Acute Physiological and Chronic Health Evaluation, CNS central nervous system, SD standard deviation, SOFA Sequential Organ Failure Assessment