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Fig. 1 | Journal of Intensive Care

Fig. 1

From: Serial change of C1 inhibitor in patients with sepsis: a prospective observational study

Fig. 1

Comparison of the serial changes of C1-INH activity between the three groups. In the non-shock group, C1-INH was 107.3 ± 26.5% on admission and 104.2 ± 22.3% on day 1, and it increased to 128.1 ± 26.4% on day 3, 138.3 ± 21.2% on day 7, and 140.3 ± 12.5% on day 14) (p < 0.0001). In the non-refractory shock group, C1-INH was 113.9 ± 19.2% on admission, and it increased thereafter to 120.2 ± 23.0% on day 1, 135.7 ± 19.9% on day 3, 138.8 ± 17.2% on day 7, and 137.7 ± 10.7% on day 14) (p < 0.0001). In the refractory shock group, C1-INH was 96.7 ± 15.9% on admission, it dropped to 88.9 ± 22.3% on day 1, and then it increased to 119.8 ± 39.6% on day 3, 144.4 ± 21.1% on day 7, and 140.5 ± 24.5% on day 14) (p < 0.0001). The difference between these three groups was statistically significant (p < 0.0001). The normal range of C1-INH activity values is 70–130%

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