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Table 1 RIFLE criteria

From: The Japanese Clinical Practice Guideline for acute kidney injury 2016

  GFR criteria Urine output criteria
Risk Increase in sCr ≥ 1.5 × baseline or decrease in GFR ≥ 25% UO < 0.5 mL/kg/h × 6 h
Injury Increase in sCr ≥ 2.0 × baseline or decrease in GFR ≥ 50% UO < 0.5 mL/kg/h × 12 h
Failure Increase in sCr ≥ 3.0 × baseline or an absolute sCr ≥ 4.0 mg/dL with an acute rise of at least 0.5 mg/dL or decrease in GFR ≥ 75% UO < 0.3 mL/kg/h × 24 h or anuria × 12 h
Loss Complete loss of kidney function > 4 weeks
ESKD End-stage renal disease (dialysis dependent > 3 months)
  1. GFR glomerular filtration rate, sCr serum creatinine, ESKD end-stage kidney disease, UO urine output