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Table 4 Univariate and multivariate analyses for better in-hospital and out-of-hospital overall survival

From: Comparison of extracorporeal membrane oxygenation outcome for influenza-associated acute respiratory failure in Japan between 2009 and 2016

Variable β HR (95%CI) p value
Univariate analysis
 Use of ECMO in 2016 1.85 6.33 (1.35–33.3) 0.019
 Baseline PaO2/FIO2Baseline PaO2/FIO2 0.05 1.05 (0.98–1.11) 0.15
 Lowest PaO2/FIO2Lowest PaO2/FIO2 0.03 1.03 (0.98–1.08) 0.27
 Highest PEEP (cmH2O) Highest PEEP (cmH2O) − 0.07 0.93 (0.85–1.02) 0.12
 Maximum SOFA score − 0.15 0.86 (0.76–0.96) 0.010
 Use of peramivir 0.81 2.25 (0.68–7.14) 0.18
 Use of oseltamivir − 0.85 0.43 (0.12–1.47) 0.18
 Use of APRV − 0.36 0.70 (0.18–2.63) 0.60
 Size of drainage cannula − 0.16 0.85 (0.43–1.69) 0.65
 Size of return cannula 0.20 1.22 (0.57–2.63) 0.60
Multivariate analysis
 Use of ECMO in 2016 1.98 7.25 (1.35–33.3) 0.021
 Maximum SOFA score − 0.21 0.81 (0.69–0.95) 0.011
  1. HR hazard ratio, CI confidence interval, ECMO, extracorporeal membrane oxygenation, PaO2/FIO2 partial pressure of arterial oxygen/fraction of inspiratory oxygen ratios, PEEP positive end-expiratory pressure, SOFA sequential organ failure assessment, APRV airway pressure release ventilation
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