|
Variable
|
β
|
HR
|
(95%CI)
|
p value
|
|---|
|
Univariate analysis
|
|
Use of ECMO in 2016
|
1.85
|
6.33
|
(1.35–33.3)
|
0.019
|
|
Baseline PaO2/FIO2Baseline PaO2/FIO2
|
0.05
|
1.05
|
(0.98–1.11)
|
0.15
|
|
Lowest PaO2/FIO2Lowest PaO2/FIO2
|
0.03
|
1.03
|
(0.98–1.08)
|
0.27
|
|
Highest PEEP (cmH2O) Highest PEEP (cmH2O)
|
− 0.07
|
0.93
|
(0.85–1.02)
|
0.12
|
|
Maximum SOFA score
|
− 0.15
|
0.86
|
(0.76–0.96)
|
0.010
|
|
Use of peramivir
|
0.81
|
2.25
|
(0.68–7.14)
|
0.18
|
|
Use of oseltamivir
|
− 0.85
|
0.43
|
(0.12–1.47)
|
0.18
|
|
Use of APRV
|
− 0.36
|
0.70
|
(0.18–2.63)
|
0.60
|
|
Size of drainage cannula
|
− 0.16
|
0.85
|
(0.43–1.69)
|
0.65
|
|
Size of return cannula
|
0.20
|
1.22
|
(0.57–2.63)
|
0.60
|
|
Multivariate analysis
|
|
Use of ECMO in 2016
|
1.98
|
7.25
|
(1.35–33.3)
|
0.021
|
|
Maximum SOFA score
|
− 0.21
|
0.81
|
(0.69–0.95)
|
0.011
|
- HR hazard ratio, CI confidence interval, ECMO, extracorporeal membrane oxygenation, PaO2/FIO2 partial pressure of arterial oxygen/fraction of inspiratory oxygen ratios, PEEP positive end-expiratory pressure, SOFA sequential organ failure assessment, APRV airway pressure release ventilation
