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Table 4 Univariate and multivariate analyses for better in-hospital and out-of-hospital overall survival

From: Comparison of extracorporeal membrane oxygenation outcome for influenza-associated acute respiratory failure in Japan between 2009 and 2016

Variable

β

HR

(95%CI)

p value

Univariate analysis

 Use of ECMO in 2016

1.85

6.33

(1.35–33.3)

0.019

 Baseline PaO2/FIO2Baseline PaO2/FIO2

0.05

1.05

(0.98–1.11)

0.15

 Lowest PaO2/FIO2Lowest PaO2/FIO2

0.03

1.03

(0.98–1.08)

0.27

 Highest PEEP (cmH2O) Highest PEEP (cmH2O)

− 0.07

0.93

(0.85–1.02)

0.12

 Maximum SOFA score

− 0.15

0.86

(0.76–0.96)

0.010

 Use of peramivir

0.81

2.25

(0.68–7.14)

0.18

 Use of oseltamivir

− 0.85

0.43

(0.12–1.47)

0.18

 Use of APRV

− 0.36

0.70

(0.18–2.63)

0.60

 Size of drainage cannula

− 0.16

0.85

(0.43–1.69)

0.65

 Size of return cannula

0.20

1.22

(0.57–2.63)

0.60

Multivariate analysis

 Use of ECMO in 2016

1.98

7.25

(1.35–33.3)

0.021

 Maximum SOFA score

− 0.21

0.81

(0.69–0.95)

0.011

  1. HR hazard ratio, CI confidence interval, ECMO, extracorporeal membrane oxygenation, PaO2/FIO2 partial pressure of arterial oxygen/fraction of inspiratory oxygen ratios, PEEP positive end-expiratory pressure, SOFA sequential organ failure assessment, APRV airway pressure release ventilation