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Table 3 Evolution of ventilatory settings and gas exchanges in 16 ARDS patients

From: Daily use of extracorporeal CO2 removal in a critical care unit: indications and results

Ventilatory parameters Baseline 4 h 8 h 12 h 24 h 48 h
Ventilatory mode (VC/PSV), number 16/0 16/0 16/0 16/0 15/1 14/2
TV (mL kg−1) 5.3 [4.4–5.9] 3.8 [3.5–4.1]* 3.7 [3.5–4.1]* 3.7 [3.6–4.1]* 3.9 [3.5–4.2]* 3.8 [3.3–4.1]*
RR (min−1) 26 [22–28] 23 [20–25] 22 [19–25]* 22 [20–25]* 21 [18–23]* 23 [17–26]
Minute ventilation (L min−1) 8.5 [6.0–9.5] 5.2 [4.0–6.1]* 4.5 [3.9–6.3]* 4.3 [3.9–6.3]* 4.6 [3.9–5.8]* 5.3 [4.0–6.9]*
PEEP (cmH2O) 13 [10–15] 14 [10–15] 14 [10–18] 14 [10–18] 14 [12–18] 14 [11–17]
Plateau pressure (cmH2O) 26 [24–27]    26 [22–29] 25 [22–27]
Driving pressure (cmH20) 10 [8–15] 7 [6–10]* 9 [8–10]*
PaCO2 (kPa) 6.7 [6.1–7.5] 5.7 [5.1–7.0]* 5.6 [4.8–7.6] 5.4 [4.8–8.2]
pH 7.31 [7.25–7.41] 7.39 [7.30–7.42] 7.40 [7.33–7.45] 7.41 [7.35–7.43]
PaO2/FiO2 145 [116–161] 207 [127–226]* 182 [149–211] 201 [168–263]*
Neuromuscular blockers use, number 15 (94%) 13 (81%) 9 (56%)
  1. *p < 0.05 vs baseline; V volume control, PSV pressure support ventilation; numbers are n (%) and median (interquartile range)