Self-reported fatigue following intensive care of chronically critically ill patients: a prospective cohort study

Table 3 Multivariable linear regression (stepwise) showing significant sociodemographic, clinical, and psychological variables of total fatigue as measured with the MFI-20 in chronically critically ill patients (N = 91) 6 months following the discharge from ICU at acute care hospital. The final model was controlled for age and gender

Multivariable linear regression^a
	Beta	CI	p value
Sociodemographic variables
Gender (male vs. female)	− .23	− .91–(−).11	.013*
Clinical variables
Number of medical comorbidities	.18	.00–.35	.045*
Psychological variables 6 months following ICU
Diagnosis of major depression according to SCID I	.44	.80–1.87	< .001**
Prior psychiatric history
History of anxiety disorder	.32	.55–1.85	< .001**
R² (corrected): .318 (F(4, 90) = 11.497, p < .001)

^aMethod stepwise; number of medical comorbidities and PTSD at t3/family status were significantly correlated (point biserial coefficient = .251, p = .016/.380, p < .001). For parsimony of the final model and to prevent multicollinearity, PTSD at t3 and family status were not considered in the final model. Tolerance/variance inflation factor and condition number test did not indicate multicollinearity
MFI-20 Multidimensional Fatigue Inventory, SCID I Structured Clinical Interview according to DSM IV
*p ≤ .05, **p ≤ .001

ISSN: 2052-0492