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Table 2 Multivariable linear regression (stepwise) showing significant clinical and psychological variables of total fatigue as measured with the MFI-20 in chronically critically ill patients (n = 113) 3 months following the discharge from ICU at acute care hospital. The final model was controlled for age and gender

From: Self-reported fatigue following intensive care of chronically critically ill patients: a prospective cohort study

Multivariable linear regressiona
  Beta CI p value
Clinical variables
 Coronary heart disease .27 .23–1.03 .002**
Psychological variables at (post-acute) ICU
 Perceived fear of dying at ICU .25 .08–.42 .005**
Psychological variables 3 months following ICU
 Diagnosis of major depression according to SCID I .26 .31–1.56 .004**
 Perceived social support according to MSPSS − .18 − .35–(−).01 .043*
R2 (corrected): .201 (F(4, 108) = 7.771, p < .001)    
  1. aMethod stepwise; PTSD at t2 and perceived fear of dying at ICU were significantly correlated (point biserial coefficient = .242, p = .011); family status and MSPSS at t2 were significantly correlated (point biserial coefficient = − .264, p = .005). Number of medical comorbidities and diagnosis of major depression/coronary heart disease were significantly correlated (point biserial coefficient = .279, p = .003/.305, p = .001). For parsimony of the final model and to prevent multicollinearity, PTSD at t2, family status and number of medical diagnoses were not considered in the final model. Tolerance/variance inflation factor and condition number test did not indicate multicollinearity
  2. MFI-20 Multidimensional Fatigue Inventory, MSPSS Multidimensional Scale of Perceived Social Support, PTSD posttraumatic stress disorder, SCID I Structured Clinical Interview according to DSM IV
  3. *p ≤ .05, **p ≤ .01