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Table 1 Patient characteristics

From: Effect of norepinephrine dosage on mortality in patients with septic shock

  L group
(n = 56)
H group
(n = 56)
p value
Age, years 70.8 ± 13.4 70.5 ± 14.4 0.92
Male sex, n (%) 33 (58) 36 (64) 0.56
Body weight, kg 53.9 ± 11.2 54.7 ± 11.9 0.72
COPD (%) 4 (7.1) 3 (5.3) 0.70
Soft tissue infection (%) 4 (7.1) 4 (7.1) 1.00
Emergency surgery (%) 28 (50.1) 23 (41.1) 0.34
Site of infection (%)
 Lung 16 (29) 13 (23)  
 Abdomen 29 (52) 23 (41)  
 Urinary tract 4 (7) 8 (14)  
 Skin and soft tissue 1 (2) 6 (11)  
 Others 6 (11) 6 (11)  
APACHE II score 25 (19, 33) 25 (20, 30) 0.89
SOFA score 10 (8, 12) 10 (8, 12) 0.63
SOFA-R score 2 (1, 3) 2 (1, 3) 0.65
SOFA-P score 0.5 (0, 2) 1 (0, 2) 0.23
SOFA-L score 0 (0, 1) 0 (0, 1) 0.65
SOFA-C score 3 (3, 4) 4 (3, 4) 0.007
SOFA-N score 0 (0, 3) 1 (0, 2) 0.63
SOFA-K score 1.5 (0, 3) 1 (0, 2) 0.34
Systolic BP, mmHg 109 (26) 105 (28) 0.31
Mean BP, mmHg 73 (16) 72 (18) 0.75
Lactate level, mmol/L 4.5 (3.0, 7.8) 4.4 (3.6, 6.6) 0.94
Urine output, mL/day 1240 (298, 2302) 1279 (378, 2566) 0.84
WBC, mm3 8500 (4500, 14,109) 5000 (2250, 13,930) 0.18
FDP, μg/dL 15.8 (7.5, 28.0) 23.6 (10.5, 52) 0.02
Fibrinogen, mg/dL 337 (243, 532) 403 (271, 583) 0.26
CRP, mg/dL 11.9 (5.2, 24.4) 16.1 (5.4, 27.3) 0.76
PCT, ng/mL 29.3 (3.2, 81.5) 40.0 (12.9, 100) 0.11
Catecholamine
 Total dopamine dosage (μg/kg) 15,727 (6180, 36,150) 28,532 (12,321, 43,407) 0.15
 Total dobutamine dosage (μg/kg) 6191 (3652, 14,796) 23,051 (13,931, 35,760) 0.003
Total vasopressin dosage (IU) 9.8 (5.1, 15.4) 30.2 (12, 54.2) 0.05
Hospital length of stays, days 29 (31) 33 (29) 0.12
Renal replacement therapy (%) 18 (32) 32 (57) 0.008
  1. Data are shown as mean ± SD, number of subjects (%), or median (IQR), as appropriate
  2. SD standard deviation, COPD chronic obstructive pulmonary disease, IQR interquartile range, APACHE II Acute Physiology and Chronic Health Evaluation II, SOFA Sequential Organ Failure Assessment, SOFA-R Sequential Organ Failure Assessment Respiration score, SOFA-P Sequential Organ Failure Assessment Coagulation score, SOFA-L Sequential Organ Failure Assessment Liver score, SOFA-C Sequential Organ Failure Assessment Cardiovascular score, SOFA-N Sequential Organ Failure Assessment Central nervous system score, SOFA-K Sequential Organ Failure Assessment Renal score, BP blood pressure, WBC white blood cell, FDP fibrinogen degradation products, CRP C-reactive protein, PCT procalcitonin