Table 1 Patient characteristics
From: Effect of norepinephrine dosage on mortality in patients with septic shock
L group (n = 56) | H group (n = 56) | p value | |
|---|---|---|---|
Age, years | 70.8 ± 13.4 | 70.5 ± 14.4 | 0.92 |
Male sex, n (%) | 33 (58) | 36 (64) | 0.56 |
Body weight, kg | 53.9 ± 11.2 | 54.7 ± 11.9 | 0.72 |
COPD (%) | 4 (7.1) | 3 (5.3) | 0.70 |
Soft tissue infection (%) | 4 (7.1) | 4 (7.1) | 1.00 |
Emergency surgery (%) | 28 (50.1) | 23 (41.1) | 0.34 |
Site of infection (%) | |||
Lung | 16 (29) | 13 (23) | |
Abdomen | 29 (52) | 23 (41) | |
Urinary tract | 4 (7) | 8 (14) | |
Skin and soft tissue | 1 (2) | 6 (11) | |
Others | 6 (11) | 6 (11) | |
APACHE II score | 25 (19, 33) | 25 (20, 30) | 0.89 |
SOFA score | 10 (8, 12) | 10 (8, 12) | 0.63 |
SOFA-R score | 2 (1, 3) | 2 (1, 3) | 0.65 |
SOFA-P score | 0.5 (0, 2) | 1 (0, 2) | 0.23 |
SOFA-L score | 0 (0, 1) | 0 (0, 1) | 0.65 |
SOFA-C score | 3 (3, 4) | 4 (3, 4) | 0.007 |
SOFA-N score | 0 (0, 3) | 1 (0, 2) | 0.63 |
SOFA-K score | 1.5 (0, 3) | 1 (0, 2) | 0.34 |
Systolic BP, mmHg | 109 (26) | 105 (28) | 0.31 |
Mean BP, mmHg | 73 (16) | 72 (18) | 0.75 |
Lactate level, mmol/L | 4.5 (3.0, 7.8) | 4.4 (3.6, 6.6) | 0.94 |
Urine output, mL/day | 1240 (298, 2302) | 1279 (378, 2566) | 0.84 |
WBC, mm3 | 8500 (4500, 14,109) | 5000 (2250, 13,930) | 0.18 |
FDP, μg/dL | 15.8 (7.5, 28.0) | 23.6 (10.5, 52) | 0.02 |
Fibrinogen, mg/dL | 337 (243, 532) | 403 (271, 583) | 0.26 |
CRP, mg/dL | 11.9 (5.2, 24.4) | 16.1 (5.4, 27.3) | 0.76 |
PCT, ng/mL | 29.3 (3.2, 81.5) | 40.0 (12.9, 100) | 0.11 |
Catecholamine | |||
Total dopamine dosage (μg/kg) | 15,727 (6180, 36,150) | 28,532 (12,321, 43,407) | 0.15 |
Total dobutamine dosage (μg/kg) | 6191 (3652, 14,796) | 23,051 (13,931, 35,760) | 0.003 |
Total vasopressin dosage (IU) | 9.8 (5.1, 15.4) | 30.2 (12, 54.2) | 0.05 |
Hospital length of stays, days | 29 (31) | 33 (29) | 0.12 |
Renal replacement therapy (%) | 18 (32) | 32 (57) | 0.008 |