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Table 4 Factors associated with 28-day mortality in adult patients with sepsis

From: Utility of SOFA score, management and outcomes of sepsis in Southeast Asia: a multinational multicenter prospective observational study

Factors

Outcome

Odds ratio (95% CI)*

Non-survivors

(n = 99)

Survivors

(n = 355)

Univariable analysis

Multivariable analysis

Admitted directly to ICU

19 (19%)

51 (14%)

3.8 (1.8–8.1, p < 0.001)

1.9 (0.8–4.5, p = 0.16)

Administered parenteral antibiotics

87 (88%)

257 (72%)

3.4 (1.6–7.0, p = 0.001)

1.7 (0.7–3.9, p = 0.22)

Administered ≥ 1500 mL fluid for hypotension or lactate ≥ 4 mmol/L

32/72 (44%)

83/159 (52%)

0.9 (0.5–1.7, p = 0.73)

0.8 (0.4–1.5, p = 0.43)

Administered adrenergic agent for hypotension

40/52 (77%)

95/139 (68%)

1.7 (0.8–3.6, p = 0.20)

1.4 (0.6–3.1, p = 0.45)

  1. *Stratified by study sites
  2. Adjusted for age and total SOFA score
  3. Denominator is total n unless otherwise specified