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Table 4 Factors associated with 28-day mortality in adult patients with sepsis

From: Utility of SOFA score, management and outcomes of sepsis in Southeast Asia: a multinational multicenter prospective observational study

Factors Outcome Odds ratio (95% CI)*
Non-survivors
(n = 99)
Survivors
(n = 355)
Univariable analysis Multivariable analysis
Admitted directly to ICU 19 (19%) 51 (14%) 3.8 (1.8–8.1, p < 0.001) 1.9 (0.8–4.5, p = 0.16)
Administered parenteral antibiotics 87 (88%) 257 (72%) 3.4 (1.6–7.0, p = 0.001) 1.7 (0.7–3.9, p = 0.22)
Administered ≥ 1500 mL fluid for hypotension or lactate ≥ 4 mmol/L 32/72 (44%) 83/159 (52%) 0.9 (0.5–1.7, p = 0.73) 0.8 (0.4–1.5, p = 0.43)
Administered adrenergic agent for hypotension 40/52 (77%) 95/139 (68%) 1.7 (0.8–3.6, p = 0.20) 1.4 (0.6–3.1, p = 0.45)
  1. *Stratified by study sites
  2. Adjusted for age and total SOFA score
  3. Denominator is total n unless otherwise specified